EMF-induced mesenchymal stem cell migration is mediated by SOCE-dependent calcium influx and modulated by ROCK signaling.
Research
RF Safe Research Library
Jan 1, 2026
This in vitro study exposed rat bone marrow-derived mesenchymal stem cells to a 50 Hz, 5 mT sinusoidal EMF and assessed migration and signaling mechanisms. The authors report increased MSC migration that depended on extracellular Ca²⁺ influx and was abolished by SOCE inhibition, alongside increased Orai1 expression…
Electrical oscillations in microtubules
Research
RF Safe Research Library
Jan 1, 2025
This study introduces a multi-scale electrokinetic model to characterize electrical impulses and ionic current propagation along microtubules, incorporating atomistic protein details and biological environments. It emphasizes nanopore-mediated coupling between microtubule surfaces as a key mechanism enabling luminal…
Human osteosarcoma cells in response to ELF-MF: Morphological remodeling compared to cell proliferation.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed human osteosarcoma (MG-63) cells to 2 mT extremely low-frequency magnetic fields with sinusoidal, triangular, or pulsed waveforms under continuous (3 h) or fractionated (3 days) conditions. The authors report significant decreases in proliferation and shape index in exposed cells versus…
Extremely low frequency electromagnetic fields promote mesenchymal stem cell migration by increasing intracellular Ca and activating the FAK/Rho GTPases signaling pathways in vitro.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human bone marrow-derived mesenchymal stem cells to extremely low frequency EMF (7.5–70 Hz, 1 mT) generated by Helmholtz coils. The authors report increased MSC migration across all tested frequencies. Mechanistically, the effect is described as dependent on intracellular calcium and…
Calreticulin attenuated microwave radiation-induced human microvascular endothelial cell injury through promoting actin acetylation and polymerization.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human microvascular endothelial cells to high-power microwave radiation at multiple power densities for 6 minutes and assessed cellular injury and cytoskeletal outcomes. The authors report dose-dependent injury from microwave exposure, including increased LDH leakage and reduced viability…