Archive
8 postsThe International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
This PubMed-listed animal study reports results from the Japanese arm of an international Japan–Korea collaboration evaluating whether long-term mobile-phone-like RF-EMF exposure causes cancer or genetic damage in rats. Male Sprague Dawley rats were exposed to 900 MHz CDMA-modulated RF-EMF at a whole-body SAR of 4 W/kg for nearly 18.5 hours/day over two years, alongside OECD/GLP genotoxicity and carcinogenicity testing. The authors report no statistically significant increases in neoplastic or non-neoplastic lesions in major organs and no evidence of DNA or chromosomal damage, concluding the findings do not support reproducible carcinogenic or genotoxic effects under these conditions.
The International Collaborative Animal Study of Mobile Phone Radiofrequency Radiation Carcinogenicity and Genotoxicity: The Japanese Study
This international collaborative animal study (Japanese arm) evaluated carcinogenicity and genotoxicity in male Sprague Dawley rats exposed long-term to 900 MHz CDMA-modulated RF-EMFs at 4 W/kg whole-body SAR. The abstract reports no statistically significant increases in neoplastic or non-neoplastic lesions in major organs and no evidence of genotoxicity on comet or micronucleus testing. The authors conclude the findings provide strong evidence of no reproducible carcinogenic or genotoxic effects under the studied conditions.
The animal carcinogenicity evidence is no longer reasonably dismissible
RF Safe argues that animal evidence for RF-related carcinogenicity is now strong and should not be dismissed, citing the NTP (2018) and Ramazzini (2018) lifetime rodent studies as showing statistically significant increases in the same rare tumor types (heart schwannomas and brain gliomas). The post further claims that effects occurred at relatively low whole-body SAR levels and references additional mechanistic hypotheses (e.g., VGCC-related models and radical-pair/spin effects) and a reported human ultrasound observation of acute non-thermal changes. These points are presented as supporting a shift away from a “thermal-only” interpretation, but the item is advocacy/commentary and does not provide full methodological details in the excerpt.
What the strongest literature actually shows now
This RF Safe article argues that the “strongest” RF-EMF literature supports concern about cancer-related findings, emphasizing non-monotonic dose–response patterns in the U.S. National Toxicology Program (NTP) rat study and citing additional analyses and animal studies. It reports that FDA evaluations have downplayed the human relevance of NTP results due to high exposures and inconsistencies, and counters that some effects may occur at lower exposure levels than commonly claimed. The piece also references the Ramazzini Institute rat study as supportive evidence at lower whole-body SARs and mentions a 2024 PLOS ONE paper analyzing Ramazzini tumors, but provides limited detail in the excerpt.
Radio Frequency Exposure in Military Contexts: A Narrative Review of Thermal Effects and Safety Considerations
This narrative review focuses on RF exposure in military contexts, emphasizing thermal effects as the established mechanism of harm and discussing safety limits set by bodies such as ICNIRP and IEEE. It reports that whole-body SAR limits (≤4 W/kg) generally prevent dangerous core temperature rises, but localized heating risks may persist for tissues like skin and eyes, especially when thermoregulation is impaired. The review highlights CEM43 as a potentially useful thermal-dose metric but notes complexity for transient exposures and calls for improved models and methods across relevant frequency bands.
NTP Lite: The Japan-Korea Collaborative RF Exposure Toxicity Project [Health Matters]
This magazine article reviews the Japan-Korea "NTP Lite" RF animal toxicity collaboration and its relationship to prior NTP (2018) and Ramazzini Institute reports of RF-associated tumors in male rats. It notes NTP Lite used a single whole-body SAR of 4 W/kg and completed a two-year exposure phase in 2022, but final reporting is delayed with histopathology and genotoxicity work ongoing. The author highlights protocol harmonization across labs while raising concerns about unexplained animal deaths and physiological differences in exposed groups, and frames the broader evidence as supportive of RF-related cancer risk in laboratory animals.
Assessment of Electromagnetic Exposure to a Child and a Pregnant Woman Inside an Elevator in Mobile Frequencies
This study uses anatomically detailed computational models of a five-year-old girl, a pregnant woman in the third trimester, and a fetus to simulate mobile phone RF exposure inside an elevator cabin. Simulations at 1000 MHz and 1800 MHz across 48 configurations evaluated SAR10g, whole-body SAR, and maximum temperature. The abstract reports that configuration (positioning and phone orientation) can substantially change absorption and temperature metrics and calls for broader scenario testing to inform safety guidance for vulnerable populations.
Assessment of RF EMF Exposure to Car Driver from Monopole Array Antennas in V2V Communications Considering Thermal Characteristics
This modeling study assessed RF-EMF exposure from a 5.9 GHz V2V monopole array antenna integrated into a car roof shark-fin antenna. Using COMSOL simulations with an adult male body model inside a vehicle, the authors estimated localized and whole-body SAR and associated core temperature rise over a 30 min averaging period. Reported SAR and temperature rise values were below ICNIRP occupational thermal-based restrictions, leading the authors to conclude the exposure does not pose a threat under the studied conditions.