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Inhibition of mitochondrial NADH:ubiquinone oxidoreductase by spinning oscillating magnetic fields causes toxicity in cancer cells

This in vitro study examines a spinning oscillating magnetic field (sOMF) generated by an Oncomagnetic device and reports selective toxicity in glioma cancer cells. The abstract attributes effects to ROS-dependent inhibition of mitochondrial complex I, with downstream oxidative stress, DNA damage, cell-cycle arrest,…

Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells

This in vitro study characterized spinning oscillating magnetic field (sOMF) stimulation patterns that the authors report can induce cytotoxicity in two types of human glioma cells. The reported effect was linked to a critical rise in superoxide, and was reversed by the antioxidant Trolox, suggesting ROS involvement.…