Archive

This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to…

This in vitro study reports that a static magnetic field (SMF) combined with paramagnetic calcium-polypyrrole nanoparticles (Ca-PPy) markedly increases bactericidal activity against E. coli and S. aureus. The authors attribute the enhanced killing to increased reactive oxygen species generation and associated…

This study describes a magnetofection system using electromagnetic field (EMF) co-stimulation with iron oxide nanoparticles (IONPs) to deliver miR-21. The authors report increased transfection efficiency and promotion of osteogenesis and angiogenesis in BMSCs and HUVECs, with downstream application to…

This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…

This materials proof-of-concept study explored using radiofrequency EMF to heat magnetic nanoparticles dispersed in PLLA to modulate polymer properties. Heating was monitored by infrared camera, and polymer changes were assessed by differential scanning calorimetry and nanoindentation. The authors report that EMF…

This in vitro study fabricated PCL nanofibrous scaffolds containing cobalt-zinc ferrite nanoparticles and evaluated physicochemical/mechanical properties and cell-related outcomes. The abstract reports improved hydrophilicity, biodegradation, and stress at break with CZF-NP incorporation, and improved L929 cell…

This paper presents a theoretical model analyzing parameters that may optimize metal nanoparticle-aided EMF photothermal therapy effects on cancer cells. The model suggests efficacy depends on both electric field enhancement and thermal (hyperthermia) contributions, influenced by nanoparticle absorption properties…

This engineering/materials study tested how microwave heating power affects properties of ZnO nanoparticles produced by microwave solvothermal synthesis. Aggregate size reportedly varied (60–120 nm) with microwave power, while individual nanoparticle size and morphology remained constant (average 27 ± 3 nm) under the…

This animal and in vitro study reports a method to lyse tumor cells mechanically using targeted superparamagnetic iron oxide nanoparticles rotated by a weak alternating magnetic field. Nude mice with head and neck tumors received cetuximab-coated nanoparticles and 4 Hz field exposures for 30 minutes on alternating…

This paper describes synthesis and characterization of magnetic nanoparticles intended for tumor hyperthermia applications. It reports that the particles show relatively high specific absorption rate (22–200 W/g) under a 160 kHz alternating magnetic field at 100–500 Oe, despite low saturation magnetization. The…

This engineering study reports fabrication of a biodegradable PLLA shape-memory nanocomposite incorporating surface-modified Fe3O4 nanoparticles. The composite showed improved tensile/mechanical and shape-memory properties compared with PLLA, and shape recovery could be triggered by an alternating magnetic field.…

This in vitro study examines RF-induced heat production in citrate-capped gold nanoparticle suspensions while minimizing confounding Joule heating from ionic buffers. It reports size-dependent heating detectable only for ≤10 nm particles, with heating scaling with concentration and surface area and being attenuated…

This paper addresses heat dissipation mechanisms of magnetic nanoparticles used in targeted hyperthermia under large alternating magnetic fields. Using numerical comparisons, it reports additional features in relaxation loss for rotatable superparamagnetic nanoparticles and field-induced formation of oriented…

This engineering-focused study examines failure of needle-shaped specimens exposed to very high electric fields in field-ion microscopy. The authors report experiments indicating breakdown may be initiated by nanoparticles detached from a point anode. They propose a mechanism in which expanding cathode plasma…

This in vitro study reports that shortwave (MHz-range) RF exposure can induce strong cytotoxicity in EGFR-overexpressing human cancer cells when those cells have internalized cetuximab-targeted gold nanoparticles. Control nanoparticles showed minimal uptake and substantially lower cytotoxicity under RF exposure. An…