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Showing results for: metabolism

Differential metabolic responses of mouse Leydig and spermatogonia cells to radiofrequency electromagnetic field exposure

Research RF Safe Research Library Jan 1, 2025

This in vitro study used LC-MS metabolomics to assess how continuous versus intermittent RF-EMF irradiation affects mouse Leydig (TM3) and spermatogonia (GC-1) cells. The authors report stronger metabolic disturbances in TM3 cells under continuous exposure, including changes in amino acid and glutathione-related…

Single-cell analysis reveals the spatiotemporal effects of long-term electromagnetic field exposure on the liver

Research RF Safe Research Library Jan 1, 2025

This animal study exposed mice to 2.45 GHz electromagnetic fields daily for up to 5 months and assessed liver effects using serum tests, lipidomics, histology, and single-cell/spatiotemporal transcriptomics. The authors report that hepatic cell types differed in sensitivity, with hepatocytes, endothelial cells, and…

Electromagnetic fields regulate iron metabolism: From mechanisms to applications

Research RF Safe Research Library Jan 1, 2025

This review synthesizes evidence that electromagnetic field (EMF) exposure is associated in the literature with changes in systemic and cellular iron metabolism, with reported effects varying by EMF parameters, exposure duration, and biological context. It proposes mechanistic pathways involving iron-containing…

Growth and defense mechanism of Phaeocystis globosa exposed to extremely low frequency electromagnetic fields.

Research RF Safe Research Library Jan 1, 2025

This laboratory study exposed cultured Phaeocystis globosa to extremely low-frequency electromagnetic fields (ELF-EMF) at 0, 0.2, and 1 mT for 24 hours. The authors report increased cell density, photosynthesis, and chlorophyll a under ELF-EMF, alongside decreased protein and carbohydrate accumulation. Metabolomic…

Electromagnetic field (50 Hz) enhance metabolic potential and induce adaptive/reprogramming response mediated by the increase of N6-methyladenosine RNA methylation in adipose-derived mesenchymal stem cells in vitro.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed adipose-derived mesenchymal stem cells to a 50 Hz electromagnetic field (1.5 mT) for 24 and 48 hours and assessed cellular responses. After 24 hours, the authors report increased N6-methyladenosine RNA methylation, increased expression of multiple stem cell markers, and changes in p21 and…

The exposure to extremely low frequency electromagnetic-fields inhibits the growth and potentiates the sensitivity to chemotherapy of bidimensional and tridimensional human osteosarcoma models.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested a specific extremely low frequency electromagnetic field (ELF-EMF) on three human osteosarcoma cell lines grown in 2D and 3D spheroid models. The abstract reports that ELF-EMF exposure inhibited proliferation and altered mitochondrial metabolism in the cancer models. It also reports…

Alternating current electromagnetic field exposure lessens intramyocellular lipid accumulation due to high-fat feeding via enhanced lipid metabolism in mice.

Research RF Safe Research Library Jan 1, 2023

This mouse study tested whether alternating current electromagnetic field (EMF) exposure modifies muscle lipid accumulation during long-term high-fat feeding. Mice exposed to EMF (8 hours/day for 16 weeks; maximum 180 mT) while on a high-fat diet had lower intramyocellular lipid levels than high-fat diet controls.…

Influence of Schumann Range Electromagnetic Fields on Components of Plant Redox Metabolism in Wheat and Peas.

Research RF Safe Research Library Jan 1, 2022

This study examined whether Schumann Resonance-range ELF electromagnetic fields (7.8, 14.3, 20.8 Hz) influence redox metabolism components in wheat and pea leaves after short (30 min) and long (18 days) exposures. The authors report that short-time exposure produced more pronounced biological effects than long-time…

Lipidomic alteration and stress-defense mechanism of soil nematode Caenorhabditis elegans in response to extremely low-frequency electromagnetic field exposure.

Research RF Safe Research Library Jan 1, 2019

This animal (nematode) study exposed Caenorhabditis elegans to 50 Hz, 3 mT extremely low-frequency EMF and assessed multi-omics responses. The authors report significant lipidomic, proteomic, and transcriptomic alterations, including increased triacylglycerols. Pathway analyses suggest disrupted lipid metabolism,…

Global gene expression changes reflecting pleiotropic effects of Irpex lacteus induced by low--intensity electromagnetic field.

Research RF Safe Research Library Jan 1, 2019

This laboratory study used RNA-seq to examine how low-intensity electromagnetic field (LI-EMF) exposure affects global gene expression in the fungus Irpex lacteus. Thousands of differentially expressed genes were reported immediately after exposure, with fewer changes after 3 h and 6 h recovery, and a subset of genes…

Exposure to 2100 MHz electromagnetic field radiations induces reactive oxygen species generation in roots.

Research RF Safe Research Library Jan 1, 2017

This experimental study examined whether 2100 MHz cell phone-related RF-EMF exposure affects oxidative stress markers in onion roots. After 1–4 hours of continuous-wave exposure in a single day, the study reports increased lipid peroxidation and ROS-related measures (MDA, hydrogen peroxide, superoxide anion).…

Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation.

Research RF Safe Research Library Jan 1, 2017

This study assessed whether adding extremely low-frequency electromagnetic field (ELF-EMF) exposure to a 4-week poststroke rehabilitation program affects nitric oxide (NO)-related biomarkers and patient status. Forty-eight poststroke patients were assigned to ELF-EMF versus non-ELF-EMF rehabilitation, with the…

Quantum mechanical model for the anticarcinogenic effect of extremely-low-frequency electromagnetic fields on early chemical hepatocarcinogenesis.

Research RF Safe Research Library Jan 1, 2017

This study develops a quantum-mechanical radical pair mechanism model to examine how an extremely-low-frequency electromagnetic field (ELF-EMF) might influence early chemical hepatocarcinogenesis in rats. The model evaluates singlet-state recombination and quantum yield under a low magnetic field effect, proposing…

Disordered redox metabolism of brain cells in rats exposed to low doses of ionizing radiation or UHF electromagnetic radiation.

Research RF Safe Research Library Jan 1, 2016

This animal study assessed redox-state changes in rat brain cells after long-term low-intensity ionizing radiation exposure or fractionated non-thermal UHF electromagnetic radiation. Both exposures were associated with decreased ubisemiquinone and increased NO-FeS-protein complexes, alongside increased mitochondrial…

Unraveling the effects of static magnetic field stress on cytosolic proteins of Salmonella by using a proteomic approach.

Research RF Safe Research Library Jan 1, 2016

This in vitro study examined how Salmonella enterica serovar Hadar adapts to a 200 mT static magnetic field for 9 hours using proteomics. The authors report 35 cytosolic proteins with >2-fold expression changes after exposure, spanning metabolism, oxidative stress response, energy homeostasis, translation elongation,…

Effects of microwave radiation on brain energy metabolism and related mechanisms

Research RF Safe Research Library Feb 17, 2015

This paper is a narrative review of microwave radiation and brain energy metabolism. The abstract frames the brain as a sensitive target organ and highlights mitochondrial injury and energy metabolism disorders as important in microwave radiation-induced brain damage. It aims to summarize biological effects, brain…

[Effect of Low-Intensity 900 MHz Frequency Electromagnetic Radiation on Rat Brain Enzyme Activities Linked to Energy Metabolism].

Research RF Safe Research Library Jan 1, 2015

This animal study examined low-intensity 900 MHz electromagnetic radiation (25 μW/cm2) and its effects on rat brain and blood serum enzymes linked to energy metabolism. The authors report that brain creatine kinase activity was the most radiosensitive among the enzymes measured and propose it as a marker of RF…

The effect of electromagnetic radiation emitted by display screens on cell oxygen metabolism - in vitro studies.

Research RF Safe Research Library Jan 1, 2015

This in vitro study exposed human blood platelet suspensions to 1 kHz electromagnetic fields at 150 or 220 V/m for 30 or 60 minutes. The authors report increased ROS and MDA (at 220 V/m, 30 min) and decreased antioxidant enzyme activities (SOD-1 and catalase), with the largest changes at 220 V/m for 60 minutes. They…

Effect of 950 MHz UHF electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the livers of young rats of different ages

Research RF Safe Research Library Jan 1, 2014

This animal study exposed rats of different early-life ages to 950 MHz UHF electromagnetic radiation for 30 minutes per day (SAR 1.0–1.3 W/kg) across gestation and/or early postnatal periods. The authors report no evidence of oxidative stress by TBARS or protein carbonyls, but report changes in fatty acid…

[Effect of low-intensity 900 MHz frequency electromagnetic radiation on rat liver and blood serum enzyme activities].

Research RF Safe Research Library Jan 1, 2014

This animal study compared rat liver and blood serum enzyme activities after a total two-hour exposure to low-intensity 900 MHz electromagnetic fields delivered as either a single or fractional schedule. The authors report that creatine kinase (liver and serum) and serum alkaline phosphatase were the most sensitive…

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