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6 postsThe effects of electrical stimulation on neurons and glia of the central nervous system
This review synthesizes evidence on how direct current and alternating current electrical stimulation affect neurons and glia in the central nervous system, spanning basic research and clinical translation. It reports polarity- and parameter-dependent effects on axonal growth, along with immunomodulatory glial responses that may favor regeneration and enhanced myelination via OPC differentiation. The authors note early clinical applications with potential longer-term functional improvements, while emphasizing that stimulation parameters and patient context can influence risks and benefits.
Effect of Static Electromagnetic Field on Growth Parameters, Survival Rate, Sex Distribution, Ratio, and Liver and Gonadal Health of Zebrafish
This animal study exposed zebrafish embryos to static electromagnetic fields for 63 days post-hatching across aquariums positioned 30–99 cm from the source, with an EMF-free control. The abstract reports strong shifts in sex distribution (including 100% female at the closest distance), markedly reduced survival in exposed groups, and histological liver and gonadal damage. The authors frame the findings as evidence of potential ecological risk via disrupted sex ratios and compromised health.
Exploring research trends in health effects of 5G antennas: a bibliometric analysis
This paper presents a bibliometric analysis of Web of Science literature (2012–2025) on potential health effects related to 5G antennas. It reports a marked increase in publications in the past five years, with substantial attention to dosimetric metrics (SAR and power density) and their regulatory limits. The authors forecast continued growth in the field and emphasize the need for ongoing research and interdisciplinary collaboration focused on potential health risks and compliance.
Mitigation of 3.5 GHz Electromagnetic Field-Induced BV2 Microglial Cytotoxicity by Polydeoxyribonucleotide
This in vitro study exposed BV2 mouse microglial cells to 3.5 GHz EMF for 2 hours and reports reduced cell growth and increased apoptosis alongside oxidative stress and signaling changes. The authors report that ROS generation and activation of JNK-1/2 and p38 MAPK were key events in the observed cytotoxicity. Polydeoxyribonucleotide (PDRN) reportedly reduced several EMF-associated cytotoxicity markers, suggesting a potential mitigating effect under the tested conditions.
The proliferation rates of HT-1080 human fibrosarcoma cells can be accelerated or inhibited by weak static and extremely low frequency magnetic fields
This in vitro study exposed HT-1080 human fibrosarcoma cells for 4 days to weak extremely low frequency magnetic fields (10 μT, 12–33 Hz) superimposed on a 45 μT static field. The authors report frequency- and amplitude-dependent increases or decreases in cell growth, including sharp inversions near 16.5 Hz with small parameter changes or reversal of the static field direction. Associated changes in membrane potential, intracellular calcium, and mitochondrial superoxide are presented as supporting a bioenergetic mechanism.
Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects
This narrative review argues that non-thermal biological effects of extremely low and microwave frequency EMFs may be mediated by activation of voltage-gated calcium channels (VGCCs). It cites 23 studies in which VGCC blockers reportedly block or reduce diverse EMF effects and proposes downstream Ca2+/calmodulin-dependent nitric oxide signaling. The review discusses both potential therapeutic effects (e.g., bone growth stimulation) and potential adverse effects via oxidative stress pathways, including a reviewed example of DNA single-strand breaks.