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Inflammasome Activation and IL-1β Release Triggered by Nanosecond Pulsed Electric Fields in Murine Innate Immune Cells and Skin

Research RF Safe Research Library Jan 15, 2024

This animal and in vitro study examined whether nanosecond pulsed electric fields (200-ns pulses) activate inflammasome signaling after electroporative damage. The authors report ASC aggregation, caspase-1 activation, and IL-1β release in murine macrophages, dendritic cells, and mouse skin in vivo. They also report…

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