Role of visual and non-visual opsins in blue light-induced neurodegeneration in Drosophila melanogaster
Research
RF Safe Research Library
Jan 1, 2025
This animal study used Drosophila knockout lines to examine whether visual (Rh1) versus non-visual (Rh7) opsins contribute to blue-light-associated neural damage. Flies were continuously exposed to 488 nm blue light from egg deposition to 20 days, and brain DNA damage and vacuolisation were assessed. The study…
Electromagnetic Field Stimulation Effects on Intrinsically Disordered Proteins and Their Role in Aging and Neurodegeneration
Research
RF Safe Research Library
Jan 1, 2025
This review discusses preclinical studies suggesting non-ionizing EMF exposures can produce beneficial biological effects, while noting ongoing controversy about mechanisms. It reports evidence of EMF-associated conformational changes in intrinsically disordered proteins relevant to neurodegeneration and describes RF…
Review of the evidence on the influence of Wi-Fi 2.4 GHz radiation on oxidative stress and its possible relationship with Alzheimer's disease
Research
RF Safe Research Library
Jan 1, 2025
The review states there is no scientific consensus on whether Wi‑Fi (2.4/5 GHz) contributes to Alzheimer's disease through oxidative stress, and that existing results are mixed and inconclusive. It discusses an indirect analysis linking oxidative-stress-responsive genes after 2.4 GHz exposure with genes associated…
Sleep and Arousal Hubs and Ferromagnetic Ultrafine Particulate Matter and Nanoparticle Motion Under Electromagnetic Fields: Neurodegeneration, Sleep Disorders, Orexinergic Neurons, and Air Pollution in Young Urbanites
Research
RF Safe Research Library
Jan 1, 2025
This review/overview argues that ultrafine particulate matter and industrial nanoparticles can reach the brain and accumulate in sleep and arousal regulatory regions, including orexinergic neuron hubs. It reports that ferromagnetic particles in these regions show motion responsive to low-intensity electromagnetic…
Melatonin and omega-3 neuroprotection in prenatal rat spinal cord exposed to 900 MHz electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined prenatal 900 MHz EMF exposure (2 hours/day for 21 days) in pregnant rats and assessed spinal cord outcomes in male offspring at postnatal day 35. Volume-based stereological measures (GM/WM ratios and total spinal cord volume) did not differ significantly between groups. Microscopy reported…
Possible effects of melatonin and omega-3 on the obesity-related hypothalamic nuclei of the electromagnetic field-exposed offspring rats: a stereological and immunohistochemical analysis.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined whether prenatal exposure to a 900 MHz electromagnetic field affects obesity-related hypothalamic nuclei in male rat offspring and whether melatonin or omega-3 modifies these effects. The EMF-exposed group showed fewer neurons in the arcuate nucleus, stronger NPY immunoreactivity, and…
Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study.
Research
RF Safe Research Library
Jan 1, 2023
This animal study evaluated ketamine administration combined with extremely low-frequency electromagnetic field (ELF-EMF) exposure in a chronic unpredictable stress (CUS) rat model. The authors report that the combined treatment increased depression-like behavior and neuronal degeneration, reduced GFAP(+) cells in…
Electromagnetic field stimulation facilitates motor neuron excitability, myogenesis and muscle contractility in spinal cord transected rats.
Research
RF Safe Research Library
Jan 1, 2022
This animal study evaluated whole-body EMF stimulation in a rat model of complete spinal cord injury. Compared with SCI alone, EMF exposure for 7 or 14 days was reported to improve electrophysiological measures of motor neuron excitability and enhance soleus muscle contractile performance. Histopathology and protein…
Lasting hepatotoxic effects of prenatal mobile phone exposure.
Research
RF Safe Research Library
Jan 1, 2017
This animal study examined liver outcomes in rat offspring 60 days after prenatal exposure to a 900 MHz electromagnetic field for 24 hours/day during gestation. The exposed group showed biochemical changes consistent with oxidative stress (higher MDA, lower GSH) and elevated liver enzymes (ALT, AST). Histopathology…
Effect of radiofrequency microtenotomy on degeneration of tendons: an experimental study on rabbits.
Research
RF Safe Research Library
Jan 1, 2014
This experimental rabbit study evaluated radiofrequency microtenotomy (Rf-mt) in prostaglandin E1-induced Achilles tendon degeneration. Rf-mt increased vascularity based on histopathology and immunohistochemistry. However, the authors report no significant difference in tendon healing compared with a sham-control…