Archive
6 postsRF Safe Never Downplays Null Results
RF Safe argues that “no effect” (null) findings in RF research should be treated as informative constraints rather than dismissed, within its S4–Mito–Spin mechanistic framework. The post claims biological and exposure heterogeneity can produce nonlinear, tissue- and signal-dependent outcomes, making null results an expected pattern under many study conditions. It references a WHO-commissioned systematic review on RF-EMF and oxidative stress biomarkers as concluding the evidence is of “very low certainty,” citing bias, heterogeneity, and exposure/measurement limitations.
No Measurable Impact of Acute 26 GHz 5G Exposure on Salivary Stress Markers in Healthy Adults
This triple-blind randomized study tested whether 26.5 minutes of 26 GHz (5G) RF exposure at environmental-like levels alters salivary stress biomarkers in healthy adults. Salivary cortisol and alpha-amylase measured before, during, and after exposure did not differ between real and sham conditions. An exploratory subgroup with frequent sampling also showed biomarker stability over time. The study addresses acute exposure only and notes the need for research on repeated or long-term exposures and vulnerable groups.
Investigating the Effects of Occupational Noise and Extremely Low-Frequency Electromagnetic Field Exposure on Oxidative Response in Power Plant Workers
This occupational study compared oxidative stress biomarkers across four groups: control, noise-only, ELF-EMF-only, and combined noise plus ELF-EMF exposure in power plant workers. The combined exposure group showed higher lipid peroxidation (MDA) and lower antioxidant-related measures (GSH and TAC) versus controls, while SOD activity was reduced in the noise-only and combined groups. The authors interpret these findings as evidence linking concurrent noise and ELF-EMF exposure with increased oxidative stress and call for further research and occupational safety guidance.
Looking for Biomarkers Which May Explain Idiopathic Environmental Intolerance Attributed to EMF (IEI-EMF): Does RF-EMF Exposure Influence Salivary Cortisol Response?
This randomized, double-blind, counterbalanced provocation study tested whether short-term RF-EMF exposure alters salivary cortisol in 72 predominantly young, healthy adults. Active exposure (2 W/kg peak SAR10g in head) showed no significant effect on cortisol compared with sham, and no sex differences were observed. The authors note that results may not rule out effects in populations not studied and encourage further research into plausible biological interactions.
Pilot questionnaire survey shows the lack of diagnostic criteria for electromagnetic hypersensitivity: a viewpoint
This viewpoint reports results from a pilot questionnaire survey of 142 self-declared EHS/IEI-EMF individuals and argues that current evidence and tools do not allow a definitive medical diagnosis of sensitivity to low-level wireless radiation. It notes that many reported diagnoses appear anecdotal and that tests used lack scientific proof for detecting such sensitivity. The article also considers individual sensitivity plausible and calls for controlled provocation and biochemical studies to develop diagnostic biomarkers.
5G Radiofrequency Exposure Reduces PRDM16 and C/EBP � mRNA Expression, Two Key Biomarkers for Brown Adipogenesis
This animal study exposed juvenile and young adult Wistar rats to 5G (3.5 GHz) or 2G (900 MHz) radiofrequency fields (1.5 V/m) for 1–2 weeks and measured brown adipose tissue-related gene expression by RT-qPCR. The abstract reports significant downregulation of PRDM16 and C/EBP mRNA after 5G exposure, while UCP1-dependent thermogenesis markers were not significantly changed at the transcriptional level. The authors interpret these findings as a potential partial disruption of brown adipocyte differentiation and raise EMF safety concerns, while calling for further confirmatory research.