Archive

Non‑Thermal RF Biological Effects: Cancer Signals in Long‑Term Bioassays and Reproductive/Developmental Harm Below Heating Thresholds

Evidence synthesis of 13 curated EMF/RF studies: high‑certainty animal cancer signals (glioma, heart schwannoma), high‑certainty male fertility impacts, and developmental/reproductive findings at low SAR—showing therm…

Ion Timing Fidelity under wireless exposure — from the S4 voltage sensor to mitochondrial oxidative stress, innate activation, and organ‑level inflammation

This RF Safe article argues that pulsed, low-frequency-modulated wireless radiofrequency exposures could disrupt voltage-gated ion channel timing (via the S4 voltage sensor), leading to altered immune-cell signaling, mitochondrial oxidative stress, and downstream innate immune activation and inflammation. It presents…

Ion Timing Fidelity under RF exposure: from S4 voltage sensing to mitochondrial ROS, mtDNA release, and immune dysregulation

This RF Safe article argues that persistent low-intensity, pulsed RF exposure could disrupt the timing of voltage-gated ion channel activity by affecting the S4 voltage-sensing region, leading to downstream changes in calcium/proton signaling, mitochondrial stress, and immune dysregulation. It proposes a mechanistic…

Mechanism first explanation of how the plasma membrane potential controls immune responses

An RF Safe article argues that plasma membrane potential (Vm) is a key control variable for immune cell behavior by shaping ion driving forces, especially Ca2+ influx through CRAC channels and K+ channel–mediated hyperpolarization. It describes proposed links between Vm-regulated ion flux and downstream immune…

Inflammasome Activation and IL-1β Release Triggered by Nanosecond Pulsed Electric Fields in Murine Innate Immune Cells and Skin

This animal and in vitro study examined whether nanosecond pulsed electric fields (200-ns pulses) activate inflammasome signaling after electroporative damage. The authors report ASC aggregation, caspase-1 activation, and IL-1β release in murine macrophages, dendritic cells, and mouse skin in vivo. They also report…