Archive

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields.

This study reports that glioblastoma-specific amplitude-modulated 27.12 MHz RF electromagnetic fields (delivered intrabuccally) inhibited proliferation in several glioblastoma cell lines exposed 3 hours/day at patient-matched levels. The authors propose a mechanism involving CACNA1H and modulation of the “Mitotic…

Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF

This study describes a therapeutic use of athermal, amplitude-modulated RF EMF (27.12 MHz) at breast cancer-specific frequencies to target breast cancer brain metastases. The abstract reports tumor growth suppression in animal models and durable regression in one patient with triple negative breast cancer brain…

Hepatocellular carcinoma therapy finds a channel on the radio

This EBioMedicine commentary discusses tumour-specific amplitude-modulated RF EMF as an anti-cancer therapy for hepatocellular carcinoma and highlights Cav3.2 (CACNA1H) T-type calcium channels as a proposed mediator of the effect. It notes that the reported whole-body averaged SAR in a treated HCC patient was below…