Electromagnetic fields modulate neuronal membrane ionic currents through altered cellular calcium homeostasis.
Research
RF Safe Research Library
Jan 1, 2025
This experimental study used loose patch clamp recordings in coronal hippocampal slices to test effects of extremely low-frequency EMF exposure. A 50 Hz, 1 mT field applied for 60 minutes decreased inward and transient outward currents in CA1 pyramidal neuron membranes. Pharmacological manipulation of intracellular…
Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study.
Research
RF Safe Research Library
Jan 1, 2023
This animal study evaluated ketamine administration combined with extremely low-frequency electromagnetic field (ELF-EMF) exposure in a chronic unpredictable stress (CUS) rat model. The authors report that the combined treatment increased depression-like behavior and neuronal degeneration, reduced GFAP(+) cells in…
The Time-Dependence of Three Different Modes of ELF-EMF Stimulation on LTP at Schaffer Collateral-CA1 Synapses.
Research
RF Safe Research Library
Jan 1, 2021
This animal ex vivo study tested whether short-term 15 Hz/2 mT ELF-EMF exposure alters LTP at rat hippocampal SC-CA1 synapses. Across sinusoidal, pulsed, and rhythm-pulsed modes, the authors report reduced LTP versus control, with greater inhibition at longer exposure durations (10–60 s). Sinusoidal stimulation…
Influence of the on-line ELF-EMF stimulation on the electrophysiological properties of the rat hippocampal CA1 neurons in vitro.
Research
RF Safe Research Library
Jan 1, 2017
This paper describes an on-line ELF magnetic stimulation setup and evaluates coil field distribution using COMSOL simulations alongside physical measurements. The authors report that modeled and measured magnetic flux densities were similar, and that stimulation induced sodium channel currents and fEPSPs in rat…