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High-specificity protection against radiation-induced bone loss by a pulsed electromagnetic field.

This study reports a noninvasive pulsed-burst electromagnetic field (PEMF) approach intended to protect against radiotherapy-induced bone loss. A 15 Hz, 2 mT PEMF waveform is described as producing distinctive calcium oscillations in osteoblasts and inhibiting radiation-related bone loss while not affecting other…

Effects of single and combined low frequency electromagnetic fields and simulated microgravity on gene expression of human mesenchymal stem cells during chondrogenesis.

This in vitro study exposed human mesenchymal stem cell pellets undergoing chondrogenesis to simulated microgravity (SMG), low-frequency EMF (5 mT, 15 Hz), or both for 3 weeks. SMG significantly changed gene expression and reduced chondrogenic marker expression (including COL2A1). LF-EMF alone showed no…

Effects of electromagnetic fields on bone loss in hyperthyroidism rat model.

This animal study evaluated whether extremely low frequency EMF exposure affects bone loss in a levothyroxine-induced hyperthyroidism rat model. Rats exposed to 15 Hz/1 mT EMF plus levothyroxine showed improved bone mineral density, mechanical measures, and partially restored trabecular bone architecture compared…

Effect of electromagnetic fields on human osteoarthritic and non-osteoarthritic chondrocytes.

This in vitro study exposed human osteoarthritic and non-osteoarthritic chondrocyte pellets to a sinusoidal 15 Hz electromagnetic field at 5 mT or 8 mT for 7 days. Under 5 mT, osteoarthritic chondrocytes showed increased expression of cartilage-related genes (COL2A1 and ACAN) compared with controls, while…