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A Decision Support System for Managing Health Symptoms of Living Near Mobile Phone Base Stations

Research RF Safe Research Library Jan 1, 2024

This analytical study evaluated machine learning models (SVM and Random Forest) to predict health symptoms in adults living near mobile phone base stations. The SVM model reportedly achieved high predictive performance for headache, sleep disturbance, dizziness, vertigo, and fatigue, and outperformed Random Forest and prior models. The abstract concludes that proximity to base stations is connected with increased prevalence of several symptoms and emphasizes distance, age, and duration of residence as key predictors.

Relationship between radiofrequency-electromagnetic radiation from cellular phones and brain tumor: meta-analyses using various proxies for RF-EMR exposure-outcome assessment

Research RF Safe Research Library Jan 1, 2024

Moon et al. (2024) report a systematic review and meta-analysis on cellular phone RF-EMR and brain tumor risk. The abstract summary states elevated risks for three brain tumor types in analyses considering ipsilateral (same-side) phone use and reports increased risk with heavy and long-term use. The text also highlights disagreement with the 2024 WHO review and raises methodological concerns about WHO conclusions.

Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones

Research RF Safe Research Library Jan 1, 2018

This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart, with malignant glioma of the brain also reported as related to exposure. In females, the report concludes equivocal evidence of carcinogenic activity for both modulations based on selected tumor outcomes, and genetic toxicology findings were mixed with some comet assay increases/equivocal results but negative micronucleus assays.

Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats

Research RF Safe Research Library Mar 1, 2017

This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following a subsequent 3 Gy Co-60 gamma challenge.

Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression

Research RF Safe Research Library Jan 1, 2016

This 2016 narrative review proposes that non-thermal microwave/lower-frequency EMFs act primarily through activation of voltage-gated calcium channels (VGCCs), with calcium channel blockers reported to block EMF effects. It summarizes animal, occupational, and epidemiological literature and reports that exposures from base stations, heavy mobile phone use, and wireless smart meters are associated with neuropsychiatric symptoms, sometimes with doseresponse patterns. The author concludes that multiple lines of evidence collectively support that non-thermal microwave EMF exposures can produce diverse neuropsychiatric effects including depression.

Effects of GSM modulated radio-frequency electromagnetic radiation on permeability of blood-brain barrier in male & female rats

Research RF Safe Research Library Jan 1, 2016

This rat study examined whether pulse-modulated 900 MHz and 1800 MHz RF exposure affects blood-brain barrier permeability using Evans blue dye. The abstract reports increased permeability in male rats at both frequencies (stronger at 1800 MHz) and in female rats at 900 MHz but not at 1800 MHz. The authors suggest mobile-phone-like RF exposure could increase blood-brain barrier permeability under non-thermal conditions, while noting that further mechanistic studies are needed.

Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats

Research RF Safe Research Library Mar 19, 2015

This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1 expression and ERK dephosphorylation, proposing activation of the mkp-1/ERK pathway as a mechanism.

The effects of microwave emitted by cellular phones on ovarian follicles in rats

Research RF Safe Research Library Jan 1, 2009

This animal study examined whether prenatal exposure to mobile phone microwaves affects ovarian development in rats. Pregnant rats were exposed to a phone placed under the cage throughout pregnancy, with mostly standby exposure and brief periodic speech-mode exposure. Female pups assessed at 21 days had fewer ovarian follicles in the exposed group than in controls, which the authors interpret as a toxic effect on ovaries.

Electromagnetic fields and DNA damage

Research RF Safe Research Library Jan 1, 2009

This review discusses the comet assay and summarizes research on non-ionizing EMF exposure and DNA/chromosomal damage. It describes both positive and negative findings across studies, noting no consistent overall pattern for radiofrequency radiation (RFR). The authors nonetheless conclude that under certain exposure conditions RFR appears genotoxic and may affect DNA damage and repair, with evidence discussed as most applicable to exposures typical of cell phone use.

Cell phones and brain tumors: a review including the long-term epidemiologic data

Research RF Safe Research Library Jan 1, 2009

This paper presents a meta-analysis of 11 peer-reviewed epidemiologic studies examining long-term (>=10 years) cell phone use with laterality analyses. It reports that long-term use is associated with an approximately doubled risk of an ipsilateral brain tumor. The abstract states statistical significance for glioma and acoustic neuroma, but not for meningioma.

Biological effects from electromagnetic field exposure and public exposure standards

Research RF Safe Research Library Jan 1, 2008

This review describes public concerns and scientific reports of non-thermal biological effects from low-intensity ELF and RF exposures. It lists multiple health endpoints reported to be associated with ELF and/or RF and highlights the BioInitiative Report’s conclusion that a reasonable suspicion of risk exists at environmentally relevant levels. The authors argue that existing public exposure standards should be lowered and that mobile phone SAR guidelines should be revised based on biology and long-term risk claims.

Mobile phone use and cancer

Research RF Safe Research Library Jan 1, 2004

This narrative review discusses potential public health consequences of widespread mobile phone use and the controversy around long-term cancer risks. It states that evidence from epidemiological and experimental studies suggests long-term exposure to mobile phone emissions may be linked to a small to moderate increased risk of certain cancers, while also emphasizing that data are insufficient for a final risk assessment. The author argues that even small risks could matter at the population level and that exposure-reduction measures may be indicated given uncertainties.

Physics and biology of mobile telephony

Research RF Safe Research Library Jan 1, 2000

This review argues that current mobile-telephony safety guidelines address excessive microwave heating but may not account for potential non-thermal influences of low-intensity, pulsed radiation. It highlights an asserted oscillatory similarity between pulsed microwave signals and certain electrochemical activities in humans as a reason for concern. While acknowledging uncertainty about health consequences, it notes reported consistencies between some non-thermal effects and neurological problems described by some users and people with long-term base-station exposure.

Headaches from cellular telephones: are they real and what are the implications?

Research RF Safe Research Library Mar 1, 1998

This review discusses reports of headaches occurring with hand-held cellular telephone use and argues they are likely real and attributable to telephone emissions. It points to earlier reports of headaches from low-intensity microwave exposure and proposes biological plausibility via effects on the blood-brain barrier and dopamine-opiate systems. The author raises the possibility that such headaches could signal biologically significant effects.

The effect of pulsed and sinusoidal magnetic fields on the morphology of developing chick embryos

Research RF Safe Research Library Jan 1, 1997

This animal study reports results from five experimental campaigns over five years examining weak magnetic field exposure and morphological abnormalities in White Leghorn chick embryos. Four campaigns reported statistically significant increases in abnormality rates, while one pulsed-field campaign showed only a small, non-significant increase. Pooled analyses reported increased abnormality rates for both pulsed and 60 Hz sinusoidal exposures compared with controls, and the authors propose genetic susceptibility as a possible confounder.

Evaluation of Electrochemical Information Transfer System: I . Effect of Electric Fields on Living Organisms

Research RF Safe Research Library Jan 1, 1976

This 1976 animal study evaluated the effects of weak ELF electric fields similar to those associated with Project Seafarer on mice. The abstract reports that electric field exposure acted as a biological stressor, with effects involving the central nervous and endocrine systems. It is presented as part of broader research assessing potential physiological changes from high-power, low-frequency electromagnetic communication systems.

Bibliography of reported biological phenomena ("effects") and clinical manifestations attributed to microwave and radio-frequency radiation

Research RF Safe Research Library Jan 1, 1971

This item is a bibliography of reported biological phenomena and clinical manifestations attributed to radio-frequency and microwave radiation. It compiles over 2000 references published up to June 1971, with supplemental listings through Nov. 21, 1971, and gives particular attention to reported effects in humans. The abstract does not describe any systematic synthesis or conclusions about health effects.

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