The proliferation rates of HT-1080 human fibrosarcoma cells can be accelerated or inhibited by weak static and extremely low frequency magnetic fields
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study exposed HT-1080 human fibrosarcoma cells for 4 days to weak extremely low frequency magnetic fields (10 μT, 12–33 Hz) superimposed on a 45 μT static field. The authors report frequency- and amplitude-dependent increases or decreases in cell growth, including sharp inversions near 16.5 Hz with…
Repeated Head Exposures to a 5G-3.5 GHz Signal Do Not Alter Behavior but Modify Intracortical Gene Expression in Adult Male Mice
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined repeated asymmetrical head exposure to a 5G-modulated 3.5 GHz signal in adult male mice for six weeks. It reports no significant changes in locomotion, anxiety, or object-based memory performance under the tested conditions. However, it found statistically significant but limited cortical…
Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined ELF-EMF effects in normal cybrids and NARP cybrids carrying a pathogenic MT-ATP6 mtDNA mutation mixture. ELF-EMF did not alter mtDNA copy number or the wild-type-to-mutant mtDNA ratio, but it increased mtDNA transcription and multiple markers of mitochondrial function in NARP cybrids,…
The Impact of Mobile Phone Electromagnetic Waves on the Neurons and Blood Brain Barrier Integrity in the Chick Embryo
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed chick embryos to electromagnetic waves from a mobile phone and compared them with unexposed controls. Electron microscopy on days 10 and 15 reported neuronal and cerebellar cellular alterations in the exposed group, including features described as apoptosis and mitochondrial swelling. The…
Role of radio-frequency electromagnetic waves in causing oxidative stress
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in…
Electromagnetic field (50 Hz) enhance metabolic potential and induce adaptive/reprogramming response mediated by the increase of N6-methyladenosine RNA methylation in adipose-derived mesenchymal stem cells in vitro.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed adipose-derived mesenchymal stem cells to a 50 Hz electromagnetic field (1.5 mT) for 24 and 48 hours and assessed cellular responses. After 24 hours, the authors report increased N6-methyladenosine RNA methylation, increased expression of multiple stem cell markers, and changes in p21 and…
The exposure to extremely low frequency electromagnetic-fields inhibits the growth and potentiates the sensitivity to chemotherapy of bidimensional and tridimensional human osteosarcoma models.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study tested a specific extremely low frequency electromagnetic field (ELF-EMF) on three human osteosarcoma cell lines grown in 2D and 3D spheroid models. The abstract reports that ELF-EMF exposure inhibited proliferation and altered mitochondrial metabolism in the cancer models. It also reports…
Lipidomic alteration and stress-defense mechanism of soil nematode Caenorhabditis elegans in response to extremely low-frequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2019
This animal (nematode) study exposed Caenorhabditis elegans to 50 Hz, 3 mT extremely low-frequency EMF and assessed multi-omics responses. The authors report significant lipidomic, proteomic, and transcriptomic alterations, including increased triacylglycerols. Pathway analyses suggest disrupted lipid metabolism,…
Disordered redox metabolism of brain cells in rats exposed to low doses of ionizing radiation or UHF electromagnetic radiation.
Research
RF Safe Research Library
Jan 1, 2016
This animal study assessed redox-state changes in rat brain cells after long-term low-intensity ionizing radiation exposure or fractionated non-thermal UHF electromagnetic radiation. Both exposures were associated with decreased ubisemiquinone and increased NO-FeS-protein complexes, alongside increased mitochondrial…
Effects of microwave radiation on brain energy metabolism and related mechanisms
Research
RF Safe Research Library
Feb 17, 2015
This paper is a narrative review of microwave radiation and brain energy metabolism. The abstract frames the brain as a sensitive target organ and highlights mitochondrial injury and energy metabolism disorders as important in microwave radiation-induced brain damage. It aims to summarize biological effects, brain…
Subzero 12-hour Nonfreezing Cryopreservation of Porcine Heart in a Variable Magnetic Field.
Research
RF Safe Research Library
Jan 1, 2015
This animal organ-preservation study compared 12-hour porcine heart preservation at -3°C using a device generating a variable magnetic field versus conventional 4°C preservation. The subzero variable-magnetic-field condition showed higher myocardial ATP, lower lactate, and less mitochondrial ultrastructural damage…
Nanosecond pulse electric field activation of platelet-rich plasma reduces myocardial infarct size and improves left ventricular mechanical function in the rabbit heart.
Research
RF Safe Research Library
Jan 1, 2012
This animal and in vitro study evaluated nanosecond pulsed electric fields (nsPEF) as a nonchemical method to activate platelet-rich plasma (PRP) for cardioprotection. In rabbits undergoing brief coronary occlusion followed by reperfusion, PRP injection into ischemic myocardium was associated with reduced infarct…