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5G Radio-Frequency-Electromagnetic-Field Effects on the Human Sleep Electroencephalogram: A Randomized Controlled Study in CACNA1C Genotyped Volunteers

Research RF Safe Research Library Jan 1, 2025

This randomized, double-blind, sham-controlled study tested whether CACNA1C rs7304986 genotype modifies sleep EEG responses to 5G RF-EMF exposure. The authors report a genotype-by-exposure interaction, with 3.6 GHz exposure in T/C carriers associated with a faster NREM sleep spindle center frequency versus sham. The abstract also notes longer sleep latency in T/C compared with T/T carriers, and concludes that genetically susceptible groups may show differential physiological responses to 5G RF-EMF.

Evaluation of Personal Radiation Exposure from Wireless Signals in Indoor and Outdoor Environments

Research RF Safe Research Library Jan 1, 2025

This exposure assessment measured personal RF electric field strength in multiple indoor and outdoor micro-environments in Malaysia using an ExpoM-RF 4 meter and modeled exposure with machine learning (FCNN, XG Boost) and linear regression. Reported exposures were usually below the stated public limit (61.4 V/m), but maximum values in dense urban areas with many base stations were reported to approach 56.7365 V/m. The authors frame near-threshold maxima in high-density areas as a potential health risk and recommend caution and monitoring.

Rapid Deployment of 5G Wireless Communication and Risk Assessment on Human Health: Quid Novi?

Research RF Safe Research Library Jan 1, 2025

This review discusses the rapid deployment of 5G and the associated debate about potential human health impacts from EMF exposure, particularly at 3.5–26 GHz including millimeter waves. It emphasizes limited published studies in these exposure ranges and highlights EU-funded initiatives and research consortia aimed at closing knowledge gaps. The authors state that guidelines are generally considered adequate at present, but argue that uncertainties—especially regarding long-term exposure—support continued research and precautionary approaches.

Potential Impacts of Radiofrequency Electromagnetic Fields on the Central Nervous System, Brain Neurotransmitter Dynamics and Reproductive System

Research RF Safe Research Library Jan 1, 2025

This review discusses potential impacts of radiofrequency electromagnetic fields from technologies such as Wi‑Fi and mobile phones on the central nervous system, neurotransmitter dynamics, and reproductive health. It describes proposed mechanisms including oxidative stress, thermal effects, altered neurotransmitter activity, ion channel changes, and neuronal apoptosis, while acknowledging conflicting evidence. The authors note that Wi‑Fi RF exposure has not been confirmed to exceed safety guidelines but argue that updated standards and long-term studies are needed, particularly for children/adolescents and in the context of expanding technologies such as 5G.

An approach for annual analysis of EMF exposure in highly sensitive areas of kindergartens and schools

Research RF Safe Research Library Jan 1, 2025

This paper proposes a time-averaging approach for analyzing long-term EMF exposure using time-series data from three sensors in a regulatory monitoring network. Sensors were installed at two kindergartens and one elementary school, and analyses reported daily/weekly patterns, differences between weekdays and weekends, and site-specific annual increases/decreases. The work emphasizes the value of continuous monitoring in sensitive areas, while not directly assessing health outcomes.

Exploring the influence of Schumann resonance and electromagnetic fields on bioelectricity and human health

Research RF Safe Research Library Jan 1, 2025

This review examines links between extremely low-frequency electromagnetic fields, especially the Schumann resonance at ~7.83 Hz, and biological regulation of bioelectricity. It describes proposed mechanisms involving calcium flux modulation and downstream effects on neural activity (including EEG) and circadian rhythms. The article presents both potential benefits from controlled ELF exposures (e.g., therapeutic applications) and potential harms from artificial EMFs disrupting key physiological processes, while emphasizing the need for further research.

Effect of Occupational Exposure to Low-frequency Electromagnetic Fields on Cataract Development

Research RF Safe Research Library Jan 1, 2025

This cross-sectional epidemiologic study enrolled 100 employees of an electricity company to assess whether occupational low-frequency electromagnetic field exposure is associated with cataract development. Cataract frequency was higher in exposed versus non-exposed groups, and nuclear opacity grading differed significantly between groups. Within exposed workers, nuclear and posterior subcapsular cataract grades were associated with longer work experience, suggesting occupational exposure may be a risk factor, particularly for nuclear cataracts.

Electromagnetic wireless remote control of mammalian transgene expression

Research RF Safe Research Library Jan 1, 2025

This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to ROS-responsive promoters. In a mouse model of type 1 diabetes, implanted engineered cells expressing an EMPOWER-controlled insulin system reportedly normalized blood glucose in response to a weak magnetic field.

Impact of expectancy on fatigue by exposure to the fifth generation of mobile communication signals

Research RF Safe Research Library Jan 1, 2025

This randomized sham-controlled study in 21 healthy participants tested whether routine-level 5G RF-EMF exposure affects fatigue and EEG power, while manipulating expectancy via correct, false, or no information about exposure order. The study reports no change in EEG power with real versus sham exposure. However, self-reported fatigue varied with the conveyed information about being exposed, suggesting an expectancy/psychological priming effect on symptom reporting.

Residential exposure to magnetic field due to high-voltage power lines and childhood leukemia risk in mainland France - GEOCAP case-control study

Research RF Safe Research Library Jan 1, 2025

This French GEOCAP registry-based case-control study evaluated childhood acute leukemia risk in relation to residential proximity to high-voltage overhead power lines and modeled ELF magnetic-field exposure. It reports an increased risk for children under 5 living within 50 m of power lines, particularly when restricting to high-quality geocoded addresses. However, modeled ELF-MF exposure >0.3 µT was not associated with increased risk, and the authors suggest proximity may capture other factors and call for further research and precaution.

The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)

Research RF Safe Research Library Jan 1, 2025

This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress and other proposed biological changes. Although inconsistencies are acknowledged, the authors conclude the overall evidence suggests harmful associations and call for standardized, long-term studies and reconsideration of guidelines.

Use of Mobile and Cordless Phones and the Association with Prostate Cancer

Research RF Safe Research Library Jan 1, 2025

This pooled analysis of two prior human studies reports increased odds of prostate cancer associated with mobile phone use, with higher estimates for longer latency and higher cumulative hours. Cordless phone use is reported to show increased risk but not statistically significant overall, with one mid-range cumulative use category showing an elevated OR. The abstract also reports higher risks among men with more aggressive prostate cancer and among those with a family history of prostate cancer.

Sensation of electric fields in the Drosophila melanogaster larva

Research RF Safe Research Library Jan 1, 2025

This animal study reports that Drosophila melanogaster larvae can sense electric fields and exhibit robust electrotaxis toward the cathode in controlled environments. The authors identify head-tip sensory neurons required for this behavior and report calcium-imaging evidence that Gr66a-positive neurons encode field strength and orientation. The work supports electrosensation as a functional sensory modality in Drosophila larvae and demonstrates measurable neural and behavioral responses to electric fields under the studied conditions.

Prospective cohort study on non-specific symptoms, cognitive, behavioral, sleep and mental health in relation to electronic media use and transportation noise among adolescents (HERMES): study protocol

Research RF Safe Research Library Jan 1, 2024

This protocol describes the third wave of the HERMES prospective adolescent cohort in Switzerland, with follow-up every four months and at one year. The study will assess electronic media use, modeled RF-EMF and transportation noise exposures, and a range of outcomes including cognition, behavior, sleep, mental health, and non-specific symptoms. A subsample will undergo personal RF-EMF measurements and accelerometer-based sleep/physical activity tracking.

Role of radio-frequency electromagnetic waves in causing oxidative stress

Research RF Safe Research Library Jan 1, 2024

This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in cardiomyocytes and hepatocytes. The authors conclude that radio-frequency electromagnetic waves can induce oxidative stress and mitochondrial damage in developing embryos.

Electromagnetic Fields Act Similarly in Plants as in Animals: Probable Activation of Calcium Channels via Their Voltage Sensor

Research RF Safe Research Library Jan 1, 2016

This narrative review proposes that low-intensity microwave/lower-frequency EMFs activate plasma membrane calcium channels in animals, increasing intracellular calcium and triggering downstream signaling including oxidative stress pathways. It further suggests that EMF actions in terrestrial multicellular plants are probably similar, with plant two-pore channels proposed as plausible mediators due to a comparable voltage sensor. The abstract describes briefly reviewed plant studies as consistent with this mechanism, but does not provide detailed exposure parameters or quantitative results.

Cell phones and brain tumors: a review including the long-term epidemiologic data

Research RF Safe Research Library Jan 1, 2009

This paper presents a meta-analysis of 11 peer-reviewed epidemiologic studies examining long-term (>=10 years) cell phone use with laterality analyses. It reports that long-term use is associated with an approximately doubled risk of an ipsilateral brain tumor. The abstract states statistical significance for glioma and acoustic neuroma, but not for meningioma.

Physics and biology of mobile telephony

Research RF Safe Research Library Jan 1, 2000

This review argues that current mobile-telephony safety guidelines address excessive microwave heating but may not account for potential non-thermal influences of low-intensity, pulsed radiation. It highlights an asserted oscillatory similarity between pulsed microwave signals and certain electrochemical activities in humans as a reason for concern. While acknowledging uncertainty about health consequences, it notes reported consistencies between some non-thermal effects and neurological problems described by some users and people with long-term base-station exposure.

The effect of pulsed and sinusoidal magnetic fields on the morphology of developing chick embryos

Research RF Safe Research Library Jan 1, 1997

This animal study reports results from five experimental campaigns over five years examining weak magnetic field exposure and morphological abnormalities in White Leghorn chick embryos. Four campaigns reported statistically significant increases in abnormality rates, while one pulsed-field campaign showed only a small, non-significant increase. Pooled analyses reported increased abnormality rates for both pulsed and 60 Hz sinusoidal exposures compared with controls, and the authors propose genetic susceptibility as a possible confounder.

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