Necroptosis triggered by ROS accumulation and Ca overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivo.
Research
RF Safe Research Library
Jan 1, 2021
This animal and in vitro study examined ELF magnetic field exposure in a mouse breast tumor model and a breast cancer cell line. The authors report tumor growth suppression and reduced expression of Ki-67, CD31, VEGFR2, and MMP-9 after exposure. They also report increased IFN-γ and TNF-α and increased…
Sinusoidal electromagnetic fields accelerate bone regeneration by boosting the multifunctionality of bone marrow mesenchymal stem cells.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro and rat study evaluated sinusoidal electromagnetic field (EMF) treatment of bone marrow mesenchymal stem cells (BMSCs) seeded on 3D-printed scaffolds for repairing critical-sized calvarial defects. The authors report that EMF-treated cell scaffolds accelerated bone defect repair in rats.…
Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed HaCaT human keratinocytes to 1760 MHz RF-EMF (SAR 4.0 W/kg; 2 h/day for 4 days). The authors report increased intracellular ROS and increased expression/activity of several matrix metalloproteinases, along with increased phosphorylation of FoxO3a and ERK1/2. Cell growth/viability and…
Electromagnetic Field (EMF) Radiation Alters Estrogen Release from the Pig Myometrium during the Peri-Implantation Period.
Research
RF Safe Research Library
Jan 1, 2021
This ex vivo animal-tissue study tested whether ELF-EMF exposure (50 or 120 Hz for 2 or 4 hours) alters estrogenic activity in pig myometrium during the peri-implantation period. The authors report EMF-associated changes in estrogen-related gene transcripts and aromatase abundance, with progesterone diminishing some…
Evaluation of the neuroprotective effects of Vitamin E on the rat substantia nigra neural cells exposed to electromagnetic field: An ultrastructural study.
Research
RF Safe Research Library
Jan 1, 2021
This rat study exposed animals to a 50 Hz, 3 mT electromagnetic field and assessed oxidative stress markers and substantia nigra ultrastructure. EMF exposure was associated with higher lipid peroxidation (MDA), lower SOD activity, and TEM-detected changes in nucleus/nuclear membrane and myelin sheath. Vitamin E…
Synergic effects of extremely low-frequency electromagnetic field and betaine on in vitro osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study tested 50 Hz, 1 mT ELF-EMF exposure (8 h/day for 21 days) and betaine (10 mM) during osteogenic induction of human adipose-derived mesenchymal stem cells. The authors report ELF-EMF decreased osteogenic differentiation and reduced RUNX2 and OCN gene expression compared with non-EMF conditions.…
Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice.
Research
RF Safe Research Library
Jan 1, 2021
This animal study examined whether 8 weeks of EMF exposure affects insulin resistance and fatty liver features in db/db mice. The authors report improvements in insulin resistance markers, hepatic redox balance, and steatosis-related outcomes after EMF exposure. They also report reduced liver triglycerides and lower…
A Prospective Comparative Study of Pulsed High-Intensity Laser Therapy and Pulsed Electromagnetic Field on Chronic Nonspecific Low Back Pain.
Research
RF Safe Research Library
Jan 1, 2021
This prospective comparative study randomized 51 adults with chronic nonspecific low back pain into HILT, pulsed EMF, or control groups for 8 weeks of treatment (twice weekly). Both HILT and EMF groups showed improvements in pain, disability, and lumbar flexion range of motion after the intervention. The study…
Effect of extremely low frequency electromagnetic field parameters on the proliferation of human breast cancer.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study tested how varying ELF-EMF parameters (frequency, flux density, duration, and continuous vs switching exposure) affect breast cancer and normal breast epithelial cell lines. The authors report that an optimized switching exposure pattern (7.83 ± 0.3 Hz, 1 mT) reduced viability of MDA-MB-231 cells…
Low-frequency electromagnetic fields combined with tissue engineering techniques accelerate intervertebral fusion.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro and rat-model study evaluated sinusoidal low-frequency EMF combined with a PCL/nHA scaffold seeded with BMSCs for intervertebral fusion. The authors report enhanced osteogenic differentiation of BMSCs and pro-osteogenic effects of conditioned medium from EMF-treated BMSCs, with suggested involvement of…
Occupational Exposure to Electromagnetic Fields and Health Surveillance According to the European Directive 2013/35/EU.
Research
RF Safe Research Library
Jan 1, 2021
This review discusses mandatory health surveillance for EMF-exposed workers under EU Directive 2013/35/EU, which focuses on preventing known direct biophysical and indirect effects. It notes that long-term effects are not covered because evidence for a causal relationship is considered inadequate. The authors report…
Low-frequency electromagnetic field influences human oral mucosa keratinocyte viability in response to lipopolysaccharide or minocycline treatment in cell culture conditions.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study examined whether low-frequency electromagnetic field (LF-EMF) exposure affects viability of human oral mucosa keratinocytes. Apoptosis (early/late) and necrosis were measured by flow cytometry, including conditions with lipopolysaccharide (LPS) or minocycline. The authors report that LF-EMF, alone…
Hypothesis: Bacteria benefiting from electromagnetic field in peripheral neuropathy.
Research
RF Safe Research Library
Jan 1, 2021
This article presents a hypothesis that persistent microbiota may exist in the host nervous system and that some bacteria can benefit from electromagnetic fields. The authors suggest such colonization could weaken nerve signals and propose that EMF sensitivity might enable electromagnetic modulation of bacterial…
Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma
Research
RF Safe Research Library
Jan 1, 2021
This pooled case series evaluated amplitude-modulated 27.12 MHz RF EMF delivered via the TheraBionic P1 device (3 hours daily) in patients with advanced hepatocellular carcinoma, comparing outcomes to historical controls. The authors report longer median overall survival for Child-Pugh A patients versus comparable…
Extremely low frequency electromagnetic fields promote cognitive function and hippocampal neurogenesis of rats with cerebral ischemia.
Research
RF Safe Research Library
Jan 1, 2021
This animal study evaluated whether ELF-EMF exposure affects recovery-related outcomes after cerebral ischemia in rats. Rats exposed to 50 Hz, 1 mT ELF-EMF for 2 hours daily over 28 days showed better Morris water maze performance than untreated rats. The study also reports increased hippocampal neurogenesis markers…
Synergistic effect of electromagnetic fields and nanomagnetic particles on osteogenesis through calcium channels and p-ERK signaling.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro and animal study evaluated whether extremely low frequency EMF exposure (1 mT, 45 Hz, 8 h/day) combined with Fe-based nanomagnetic particles enhances osteogenesis. The authors report no detectable cytotoxicity and increased osteogenic markers/proteins with combined NMP + EMF exposure, alongside…
Effect of a Smartphone-Based App on the Quality of Life of Patients With Heart Failure: Randomized Controlled Trial.
Research
RF Safe Research Library
Jan 1, 2020
This randomized controlled trial evaluated whether adding a smartphone-based app to routine care improves quality of life in hospitalized patients with heart failure. Over 3 months, the app group reported significantly better quality-of-life scores than the control group on the Minnesota Living with Heart Failure…
Effect of Exposure to a Radiofrequency Electromagnetic Field on Body Temperature in Anesthetized and Non-Anesthetized Rats.
Research
RF Safe Research Library
Jan 1, 2020
This animal study examined whether anesthesia and body mass modify body temperature responses to 915 MHz RF exposure at 4 W/kg whole-body SAR for 8 hours. Non-anesthetized, free-moving rats showed no significant temperature change during exposure. In contrast, anesthetized rats showed marked temperature increases,…
[Jurisprudence on occupational radiofrequency diseases].
Research
RF Safe Research Library
Jan 1, 2020
This article reviews Italian jurisprudence on alleged occupational tumours linked to RF EMF exposure (notably from wireless phones), with some cases also involving other RF sources or ELF magnetic fields. It contrasts court decisions that recognized occupational causation with others that rejected it, emphasizing how…
[The new AIRM guidelines for workers exposed to electromagnetic fields: health surveillance and fit for work judgment].
Research
RF Safe Research Library
Jan 1, 2020
This report discusses elements of new AIRM (Italian Association of Medical Radiation Protection) guidelines for health surveillance of workers exposed to electromagnetic fields. It focuses on identifying which workers should undergo surveillance and what surveillance should include. The approach described emphasizes…
and Exposed to Wi-Fi Radiofrequency Electromagnetic Radiation Show Enhanced Growth and Lactic Acid Production.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro experimental study exposed two Lactobacillus probiotic cultures to 2.4 GHz Wi‑Fi RF-EMF from a router for 15–60 minutes and compared them with sham-exposed controls. The authors report increased bacterial growth after 30–60 minutes of exposure, with no growth difference at 15 minutes. Lactic acid…
Modelling the Influence of Electromagnetic Field on the User of a Wearable IoT Device Used in a WSN for Monitoring and Reducing Hazards in the Work Environment.
Research
RF Safe Research Library
Jan 1, 2020
This modeling study estimated SAR in a multi-layer head model from a wearable IoT device’s Wi‑Fi/Bluetooth antenna. SAR was reported to be up to 10× higher when the antenna was placed in a headband versus on a helmet. The authors suggest that devices emitting below 3 mW EIRP may be considered environmentally…
Is the Increasing Incidence of Thyroid Cancer in the Nordic Countries Caused by Use of Mobile Phones?
Research
RF Safe Research Library
Jan 1, 2020
This ecological analysis reports increasing thyroid cancer incidence over time in Sweden (1970–2017) and similarly across Nordic countries using NORDCAN data (1970–2016), with sharper increases in more recent years. The authors report similar increases for smaller (≤4 cm) and larger (>4 cm) tumors and interpret this…
Electromagnetic Field in Alzheimer's Disease: A Literature Review of Recent Preclinical and Clinical Studies.
Research
RF Safe Research Library
Jan 1, 2020
This literature review summarizes recent preclinical and clinical research on electromagnetic fields (EMF) in relation to Alzheimer's disease (AD). It describes AD pathology involving amyloid-beta accumulation and tau hyperphosphorylation and notes limitations of current symptomatic treatments. The authors report…
Causal perception is central in electromagnetic hypersensitivity - a commentary on "Electromagnetic hypersensitivity: a critical review of explanatory hypotheses''.
Research
RF Safe Research Library
Jan 1, 2020
This is a commentary on Dieudonné (2020) addressing explanatory hypotheses for electromagnetic hypersensitivity (EHS). The authors state that the electromagnetic hypothesis (EMF exposure as the cause of EHS) appears scientifically largely unfounded and that psychological-process accounts are more plausible. They…