Effects of coenzyme Q10 on sperm parameters and pathological changes induced by Wi-Fi waves in the testicular tissue of rats
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed rats to Wi‑Fi waves for 7 hours/day for 2 months and assessed sperm parameters, serum testosterone, and testicular/epididymal pathology, with and without coenzyme Q10 (CoQ10). The authors report that Wi‑Fi exposure was linked to worse sperm parameters, lower testosterone, and adverse…
Does Electromagnetic Pollution in the ART Laboratory Affect Sperm Quality? A Cross-Sectional Observational Study.
Research
RF Safe Research Library
Jan 1, 2025
This cross-sectional observational study assessed sperm motility after one hour of in vitro exposure of semen samples to EMFs from different laboratory sources in an IVF setting. It reports a statistically significant reduction in progressive sperm motility after exposure to mobile phones and Wi-Fi repeaters, while…
Exploring the impact of environmental factors on male reproductive health through epigenetics
Research
RF Safe Research Library
Jan 1, 2025
This narrative review discusses how environmental factors may affect male reproductive health through epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. It reports that electromagnetic radiation, particularly from mobile phones and wireless…
An 1800 MHz Electromagnetic Field Affects Hormone Levels, Sperm Quality, and Behavior in Laboratory Rats
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed rats to a 1800 MHz electromagnetic field for 12 weeks and assessed hormones, sperm quality, and behavior. The abstract reports increased corticosterone, decreased thyroid-stimulating hormone, reduced sperm motility/viability, and increased anxiety-like behavior in exposed rats. Some hormonal…
Melatonin ameliorates RF-EMR-induced reproductive damage by inhibiting ferroptosis through Nrf2 pathway activation
Research
RF Safe Research Library
Jan 1, 2025
This animal study reports that prolonged RF-EMR exposure (2.45 GHz for 8 weeks) increased oxidative stress and ferroptosis in mouse testicular tissue and was associated with reduced sperm quality. Melatonin administration reportedly mitigated oxidative injury and inhibited ferroptosis. The abstract attributes the…
The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)
Research
RF Safe Research Library
Jan 1, 2025
This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress…
Histomorphometry and Sperm Quality in Male Rats Exposed to 2.45 GHz Wi-Fi
Research
RF Safe Research Library
Jan 1, 2025
This animal study exposed adult male rats to 2.45 GHz Wi‑Fi from an active router for 4 or 24 hours daily over eight weeks and assessed reproductive organ histology and sperm parameters. The authors report histological changes in testes and epididymis, multifocal atypical hyperplasia in seminal vesicles, reduced…
Corrigendum to "Effects of radiofrequency electromagnetic field (RF-EMF) exposure on male fertility: A systematic review of experimental studies on non-human mammals and human sperm in vitro" [Environ. Int. 185 (2024) 108509]
Research
RF Safe Research Library
Jan 1, 2025
This 2025 corrigendum relates to a systematic review of experimental RF-EMF exposure studies on non-human mammals and human sperm in vitro. The text reports an upgrade to high certainty for the key endpoint that male RF-EMF exposure causes a significant reduction in pregnancy rate when exposed males are mated. It…
Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models
Research
RF Safe Research Library
Jan 1, 2024
This rodent study examined whether 2.45 GHz Wi‑Fi router RF-EMF exposure could mitigate heat-stress-related reproductive damage in male rats. The combined RF-EMF + heat group reportedly had improved testicular structure measures and sperm quality versus heat-only, while RF-EMF alone was also reported to alter testis…
The effects of radiofrequency exposure on male fertility: A systematic review of human observational studies with dose-response meta-analysis (SR 3)
Research
RF Safe Research Library
Jan 1, 2024
This systematic review and dose-response meta-analysis synthesizes human observational studies on radiofrequency EMF exposure and male fertility outcomes. It reports evidence of an association between RF exposure and poorer sperm parameters, including reduced quality, motility, and viability. The authors frame the…
Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on male fertility and pregnancy and birth outcomes: Protocols for a systematic review of experimental studies in non-human mammals and in human sperm exposed in vitro.
Research
RF Safe Research Library
Jan 1, 2021
This paper presents protocols for a systematic review of experimental studies assessing RF-EMF exposure (100 kHz–300 GHz) and outcomes related to male fertility and pregnancy/birth effects. The review will cover three evidence streams: non-human mammal male reproductive outcomes, human sperm exposed in vitro, and in…
The guardians of germ cells; Sertoli-derived exosomes against electromagnetic field-induced oxidative stress in mouse spermatogonial stem cells.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed mouse spermatogonial stem cells to 50 Hz EMF (2.5 mT; 1 h/day for 5 days) and assessed oxidative stress and cell health outcomes. The authors report increased ROS and apoptosis with reduced antioxidant (catalase) expression, viability, and colonization after EMF exposure. Sertoli…
Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice.
Research
RF Safe Research Library
Jan 1, 2020
This animal study exposed male BALB/c mice to 2100 MHz EMF and assessed reproductive and hormonal outcomes, including sperm parameters, testicular histology, HspA2 immunoreactivity, and apoptosis. EMF exposure was associated with increased testicular apoptosis, increased abnormal sperm, and increased HspA2…
Protective effects of luteolin on rat testis following exposure to 900 MHz electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2019
This rat study examined 900 MHz EMF exposure effects on testes and whether luteolin modifies those effects. EMF exposure was associated with reduced testicular cell counts, lower testis weight and serum testosterone, increased SOD activity, and changes in sperm morphology versus controls. Luteolin co-treatment was…
Effect of Electromagnetic Waves from Mobile Phones on Spermatogenesis in the Era of 4G-LTE.
Research
RF Safe Research Library
Jan 1, 2018
This animal experiment assessed whether long-duration 4G-LTE mobile phone electromagnetic field exposure affects spermatogenesis in male rats. After 1 month, the highest exposure condition (3 cm distance, 18 h/day) had reduced spermatid, spermatogonia, total germ cell, and Leydig cell counts compared with sham and…
Activation of TLR signalling regulates microwave radiation-mediated impairment of spermatogenesis in rat testis.
Research
RF Safe Research Library
Jan 1, 2018
This rat study examined whether microwave radiation affects Toll-like receptor (TLR) signaling in testis. The authors report increased TLR2-5 expression and elevated pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) after microwave exposure. Key phosphorylated components of TLR signaling (including NF-κB p65) were also…
Effects of Wi-Fi (2.45 GHz) Exposure on Apoptosis, Sperm Parameters and Testicular Histomorphometry in Rats: A Time Course Study
Research
RF Safe Research Library
Jan 1, 2015
This animal experimental study exposed male Wistar rats to 2.45 GHz Wi-Fi radiation for 1 or 7 hours per day over two months and compared them with unexposed controls. The abstract reports time-dependent decreases in sperm parameters alongside increased apoptotic markers (apoptosis-positive cells and caspase-3…
What is harmful for male fertility: cell phone or the wireless Internet?
Research
RF Safe Research Library
Jan 1, 2015
This cross-sectional study of men attending an infertility clinic assessed associations between self-reported mobile phone and wireless Internet use and semen parameters. Mobile phone usage period was not significantly associated with sperm count or morphology, while motility showed a borderline association. Higher…
Association between mobile phone use and semen quality: a systemic review and meta-analysis
Research
RF Safe Research Library
Jan 1, 2014
This systematic review and meta-analysis assessed whether mobile phone use or radiofrequency exposure is associated with semen quality. Across included studies, the meta-analysis found no adverse effects in human studies, but reported detrimental effects on sperm motility and viability in vitro and harmful effects on…
Effect of mobile telephones on sperm quality: a systematic review and meta-analysis
Research
RF Safe Research Library
Jan 1, 2014
This 2014 systematic review and random-effects meta-analysis evaluated whether RF-EMR from mobile phones affects human sperm quality. Across 10 studies (1492 samples), exposure was associated with reduced sperm motility and reduced viability, while findings for sperm concentration were more equivocal. The abstract…
2.45-GHz microwave irradiation adversely affects reproductive function in male mouse, Mus musculus by inducing oxidative and nitrosative stress
Research
RF Safe Research Library
Jan 1, 2014
This animal study exposed 12-week-old male Swiss strain mice to non-thermal low-level 2.45-GHz microwave radiation for 2 hours per day over 30 days (SAR 0.018 W/kg). The abstract reports reduced sperm count and viability, testicular structural changes, lower 3β-HSD activity and plasma testosterone, and increased…
[State of the reproductive systemin in male rats of 1st generation obtained from irradiated parents and exposed to electromagnetic radiation (897 MHz) during embryogenesis and postnatal development].
Research
RF Safe Research Library
Jan 1, 2014
This animal study examined prolonged 897 MHz electromagnetic radiation exposure (8 h/day) in first-generation male rats from irradiated parents, with exposure during embryogenesis and postnatal development. The abstract reports fewer births and a sex ratio shift toward more males. It also reports accelerated male…
The Effects of Cell Phone Waves (900 MHz-GSM Band) on Sperm Parameters and Total Antioxidant Capacity in Rats.
Research
RF Safe Research Library
Jan 1, 2013
This experimental study exposed adult male Wistar rats to 900 MHz GSM-band cell phone-related waves for 2 or 3 weeks and assessed sperm parameters and total antioxidant capacity. All exposure groups showed significantly reduced sperm viability, motility, and total antioxidant capacity compared with controls.…
Down-regulation of metallothionein 1 and 2 after exposure to electromagnetic field in mouse testis.
Research
RF Safe Research Library
Jan 1, 2011
This animal study examined mouse testis after 8 weeks of exposure to a 3 MT electromagnetic field (4 hours/day). The authors report significant histological changes (increased primary spermatocytes, increased Leydig cells, and increased basement membrane thickness) in exposed mice versus controls. MT1 and MT2…