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29 postsEffect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats
This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following a subsequent 3 Gy Co-60 gamma challenge.
Effects of radiofrequency radiation exposure on blood-brain barrier permeability in male and female rats
This rat study tested whether acute exposure to 0.9 and 1.8 GHz continuous-wave radiofrequency radiation alters blood-brain barrier permeability. Using Evans-blue/albumin as a tracer, the authors report no BBB leakage in exposed female rats but a significant increase in albumin in exposed male rat brains versus sham. The authors interpret this as suggesting BBB/vascular permeability changes in males at SAR levels stated to be below international limits.
Electromagnetic fields and DNA damage
This review discusses the comet assay and summarizes research on non-ionizing EMF exposure and DNA/chromosomal damage. It describes both positive and negative findings across studies, noting no consistent overall pattern for radiofrequency radiation (RFR). The authors nonetheless conclude that under certain exposure conditions RFR appears genotoxic and may affect DNA damage and repair, with evidence discussed as most applicable to exposures typical of cell phone use.
Genetic damage in mammalian somatic cells exposed to radiofrequency radiation: a meta-analysis of data from 63 publications (1990-2005)
A meta-analysis of 63 publications assessed whether radiofrequency (RF) radiation exposure is associated with genetic damage in mammalian somatic cells using multiple genotoxicity endpoints. Overall differences between RF-exposed and control conditions were reported as small, though statistically significant increases were observed for some endpoints under certain exposure conditions. Mean chromosomal aberration and micronucleus indices were reported to fall within historical spontaneous levels, and the analysis found considerable evidence of publication bias.