Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway.
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study examined 50 Hz ELF-EMF effects on human T-type calcium channels expressed in HEK293 cells and on native T-type channels in primary cultured mouse cortical neurons. The authors report that ELF-EMF (0.2 mT) inhibited Cav3.1, Cav3.2, and Cav3.3 channel activity without changing Cav3.2 expression or…
[Electromagnetic radiation of non-thermal intensity and short exposition as a sub-threshold irritant for the central nervous system].
Research
RF Safe Research Library
Jan 1, 2013
This article presents a generalization and analysis of the author's long-term materials on brain responses to low-intensity electromagnetic radiation (~500 microW/cm2, continuous or pulsed) after short exposure (~30 minutes). It describes experimental results at the level of single neurons, brain formations, and the…
Role of cortical cell type and morphology in subthreshold and suprathreshold uniform electric field stimulation in vitro.
Research
RF Safe Research Library
Jan 1, 2009
This in vitro study examined how cortical neuron morphology and cell type relate to responses under subthreshold and suprathreshold uniform electric fields in rat motor cortex slices. The authors report that morphology correlates with subthreshold somatic polarization and that layer V pyramidal neurons are predicted…
[Effect of 1.8 GHz radiofrequency electromagnetic fields on gene expression of rat neurons].
Research
RF Safe Research Library
Jan 1, 2008
This in vitro study exposed primary cultured rat neurons to 1.8 GHz RF-EMF at an average SAR of 2 W/kg and assessed gene expression changes. The authors report multiple differentially expressed genes after 24 h intermittent exposure and confirm exposure-dependent changes in Egr-1, Mbp, and Plp by semi-quantitative…