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Histomorphometric study of thyroid tissue in juvenile rats exposed to 5G electromagnetic fields

Research RF Safe Research Library Jan 1, 2025

This animal study examined thyroid histomorphometry in juvenile male Wistar rats after 2 weeks of 5G EMF exposure (3.5 GHz, 1.5 V/m). Exposed rats showed larger follicle and colloid areas and a significantly lower Thyroid Activation Index, which the authors interpret as thyroid hypoactivity. The authors suggest this may represent a potential health risk and call for further work including hormone assays and mechanistic studies.

Protective effects of quercetin against 3.5 GHz RF radiation-induced thyroid dysfunction and oxidative stress in rats

Research RF Safe Research Library Jan 1, 2025

This rat study examined repeated 3.5 GHz RF exposure (2 hours/day, 5 days/week for 30 days) and thyroid-related outcomes, with and without quercetin. The abstract reports altered thyroid hormones (lower T3/T4, higher TSH) and increased oxidative stress in thyroid tissue after RF exposure. Quercetin appeared partially protective, though effects were not uniformly statistically significant, and SAR simulations indicated relatively higher absorption in the thyroid region.

Characterization of the Core Temperature Response of Free-Moving Rats to 1.95 GHz Electromagnetic Fields

Research RF Safe Research Library Jan 1, 2025

This animal study measured core body temperature in free-moving male and female Sprague Dawley rats during and after 3-hour exposure to 1.95 GHz RF-EMF at multiple whole-body average SAR levels. A measurable thermal response was reported at 4 W/kg, while lower SAR conditions showed smaller or no significant temperature increases. The authors note that temperature dropped quickly after exposure ended, implying post-exposure measurements may underestimate peak heating.

Mitigation of 3.5 GHz Electromagnetic Field-Induced BV2 Microglial Cytotoxicity by Polydeoxyribonucleotide

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed BV2 mouse microglial cells to 3.5 GHz EMF for 2 hours and reports reduced cell growth and increased apoptosis alongside oxidative stress and signaling changes. The authors report that ROS generation and activation of JNK-1/2 and p38 MAPK were key events in the observed cytotoxicity. Polydeoxyribonucleotide (PDRN) reportedly reduced several EMF-associated cytotoxicity markers, suggesting a potential mitigating effect under the tested conditions.

SAR Estimations in a Classroom with Wireless Computers

Research RF Safe Research Library Jan 1, 2025

This study simulated 1 g and 10 g peak spatial SAR (psSAR) in classroom settings where each student uses a Wi‑Fi laptop at 2.45 GHz and 100 mW. Maximum simulated psSAR values were reported to be below ICNIRP and IEEE recommended limits, but desk spacing and multi-user configurations could substantially increase psSAR compared with a single-user setup. The authors emphasize that long-term low-level exposure, particularly for children, remains a concern and recommend mitigation via increased spacing and wired connections.

Effects of non-ionizing radiation on the thyroid gland in rats

Research RF Safe Research Library Jan 1, 2025

This animal study exposed Sprague-Dawley rats (including pregnant females and offspring) to 2.45 GHz Wi-Fi or mobile jammer radiation for 2 hours daily over two weeks and assessed thyroid hormones and thyroid histology. The abstract reports significant changes in T4 in exposed adult males and significant differences in T3 among male offspring exposed to jammer radiation. Histopathology reportedly showed disrupted thyroid follicular structure in exposed rats. The authors conclude these findings support a potential link between non-ionizing radiation exposure and altered thyroid endocrine and histological parameters.

Melatonin ameliorates RF-EMR-induced reproductive damage by inhibiting ferroptosis through Nrf2 pathway activation

Research RF Safe Research Library Jan 1, 2025

This animal study reports that prolonged RF-EMR exposure (2.45 GHz for 8 weeks) increased oxidative stress and ferroptosis in mouse testicular tissue and was associated with reduced sperm quality. Melatonin administration reportedly mitigated oxidative injury and inhibited ferroptosis. The abstract attributes the protective effect to Nrf2 pathway activation via MT1/MT2 receptors.

Assessing EMF Exposure in Greek Urban and Suburban Areas During 5G Deployment: A Focus on 5G EMF Levels and Distance Correlation

Research RF Safe Research Library Jan 1, 2025

This exposure assessment reports 400 ground-level electric field measurements in Greek urban and suburban areas during 5G deployment. It finds that 4G contributes most to overall measured EMF exposure, while 5G currently contributes less. The study reports an inverse relationship between 3.5 GHz EMF levels and distance from 5G base stations, with urban areas showing higher levels than suburban areas.

Repeated Head Exposures to a 5G-3.5 GHz Signal Do Not Alter Behavior but Modify Intracortical Gene Expression in Adult Male Mice

Research RF Safe Research Library Jan 1, 2025

This animal study examined repeated asymmetrical head exposure to a 5G-modulated 3.5 GHz signal in adult male mice for six weeks. It reports no significant changes in locomotion, anxiety, or object-based memory performance under the tested conditions. However, it found statistically significant but limited cortical gene expression changes (<1% of expressed genes), including enrichment for glutamatergic synapse-related genes and lateralized differences involving mitochondrial genome-encoded genes. The authors caution that potential health risks from these intracortical transcriptomic modifications should not be downplayed and note uncertainties about longer exposures and other populations.

5G Radiofrequency Exposure Reduces PRDM16 and C/EBP � mRNA Expression, Two Key Biomarkers for Brown Adipogenesis

Research RF Safe Research Library Jan 1, 2025

This animal study exposed juvenile and young adult Wistar rats to 5G (3.5 GHz) or 2G (900 MHz) radiofrequency fields (1.5 V/m) for 1–2 weeks and measured brown adipose tissue-related gene expression by RT-qPCR. The abstract reports significant downregulation of PRDM16 and C/EBP mRNA after 5G exposure, while UCP1-dependent thermogenesis markers were not significantly changed at the transcriptional level. The authors interpret these findings as a potential partial disruption of brown adipocyte differentiation and raise EMF safety concerns, while calling for further confirmatory research.

The CB1R of mPFC is involved in anxiety-like behavior induced by 0.8/2.65 GHz dual-frequency electromagnetic radiation

Research RF Safe Research Library Jan 1, 2025

This animal study reports that dual-frequency RF EMR exposure (0.8/2.65 GHz, 4 W/kg) induced anxiety-like behavior in mice. It also reports reduced CB1R and endocannabinoid levels in the mPFC and altered endocannabinoid system markers in the BLA. CB1R overexpression or knockdown in the mPFC reportedly decreased or increased anxiety-like behavior, respectively, suggesting a mechanistic link in this model.

Histomorphometry and Sperm Quality in Male Rats Exposed to 2.45 GHz Wi-Fi

Research RF Safe Research Library Jan 1, 2025

This animal study exposed adult male rats to 2.45 GHz Wi‑Fi from an active router for 4 or 24 hours daily over eight weeks and assessed reproductive organ histology and sperm parameters. The authors report histological changes in testes and epididymis, multifocal atypical hyperplasia in seminal vesicles, reduced seminiferous tubule diameter, and reduced spermatogenesis index in exposed groups. Sperm concentration decreased in both exposed groups, motility decreased in the 4-hour group, and viability increased in the 24-hour group, leading to an overall interpretation of potential reproductive risk under the studied conditions.

Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models

Research RF Safe Research Library Jan 1, 2024

This rodent study examined whether 2.45 GHz Wi‑Fi router RF-EMF exposure could mitigate heat-stress-related reproductive damage in male rats. The combined RF-EMF + heat group reportedly had improved testicular structure measures and sperm quality versus heat-only, while RF-EMF alone was also reported to alter testis and sperm parameters. The authors interpret the findings as potentially consistent with an adaptive response and call for more research on mechanisms and safety.

RF Shielded Hat for Protecting Cameraman from EMF Exposure

Research RF Safe Research Library Jan 1, 2014

The paper describes the development of RF-shielded hats using a microwave absorbing sheet intended to reduce EMF exposure to a cameraman’s head. Three hat designs are described, and measurements are planned/performed in an anechoic chamber using a wireless video camera operating around 1.9–2.7 GHz, including a 2.45 GHz signal condition and a sham condition. The abstract does not report quantitative results on whether exposure was reduced.

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