Evaluation of Cytotoxic and Genotoxic Effects of Extremely Low-frequency Electromagnetic Field on Mesenchymal Stromal Cells.
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RF Safe Research Library
Jan 1, 2018
This in vitro study evaluated whether a therapeutic extremely low-frequency EMF exposure (5 Hz, 0.4 mT) causes cytotoxic or genotoxic effects in a human mesenchymal stromal cell line. Cells were exposed for 20 minutes per day, three times per week, for two weeks and assessed for viability, proliferation, and…
Extremely low frequency electromagnetic fields promote mesenchymal stem cell migration by increasing intracellular Ca and activating the FAK/Rho GTPases signaling pathways in vitro.
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RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human bone marrow-derived mesenchymal stem cells to extremely low frequency EMF (7.5–70 Hz, 1 mT) generated by Helmholtz coils. The authors report increased MSC migration across all tested frequencies. Mechanistically, the effect is described as dependent on intracellular calcium and…
The effect of exposure to low frequency electromagnetic fields (EMF) as an integral part of the housing system on anxiety-related behaviour, cognition and welfare in two strains of laboratory mouse.
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RF Safe Research Library
Jan 1, 2018
This animal study tested whether continuous low-frequency EMF exposure from a cage-integrated EMF plate affected anxiety-related behaviour, cognition, or welfare over six weeks in two mouse strains. Across all measured outcomes, the authors report no significant differences between EMF on versus off conditions.…
Effects of Fifty-Hertz Electromagnetic Fields on Granulocytic Differentiation of ATRA-Treated Acute Promyelocytic Leukemia NB4 Cells.
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RF Safe Research Library
Jan 1, 2018
This in vitro study examined whether 50 Hz, 2 mT extremely low-frequency electromagnetic fields affect ATRA-driven granulocytic differentiation in NB4 acute promyelocytic leukemia cells. The authors report reduced proliferation and enhanced maturation/differentiation markers with ELF-EMF exposure. They also report…
Important parameters for optimized metal nanoparticles-aided electromagnetic field (EMF) effect on cancer.
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RF Safe Research Library
Jan 1, 2018
This paper presents a theoretical model analyzing parameters that may optimize metal nanoparticle-aided EMF photothermal therapy effects on cancer cells. The model suggests efficacy depends on both electric field enhancement and thermal (hyperthermia) contributions, influenced by nanoparticle absorption properties…
Does acute radio-frequency electromagnetic field exposure affect visual event-related potentials in healthy adults?
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RF Safe Research Library
Jan 1, 2018
This double-blind, randomized, counterbalanced study tested whether acute GSM-like 920 MHz RF-EMF exposure affects visual event-related potentials in 36 healthy adults. Compared with sham, exposure was associated with reduced P1 amplitude and increased anterior N1 latency, with no effects on other ERP measures. The…
Comparison of radiofrequency electromagnetic field exposure levels in different everyday microenvironments in an international context.
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RF Safe Research Library
Jan 1, 2018
This exposure assessment quantified RF-EMF levels using portable, high-sampling-rate devices across 94 outdoor microenvironments and 18 public transport vehicles in six countries. Mean outdoor exposure ranged from 0.23 to 1.85 V/m, and public transport exposure ranged from 0.32 to 0.86 V/m. Exposure varied…
Extremely low frequency variable electromagnetic fields affect cancer and noncancerous cells in vitro differently: Preliminary study.
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RF Safe Research Library
Jan 1, 2018
This in vitro study exposed cancer (U87-MG; 143B) and noncancerous (BJ; HEK) cells to extremely low frequency electromagnetic fields under varying frequencies (2–60 Hz), waveforms, and exposure durations, with sham controls. Cell viability was assessed using an MTT assay. The authors report that cancer and…
Case-Control Study on Occupational Exposure to Extremely Low-Frequency Electromagnetic Fields and the Association with Meningioma.
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Jan 1, 2018
This case-control analysis assessed occupational extremely low-frequency electromagnetic field (ELF-EMF) exposure and meningioma using the INTEROCC ELF-EMF job-exposure matrix. Cumulative, average, and maximum job exposure metrics were evaluated. The study reports no increased meningioma risk in any exposure…
Influence of Radiofrequency Electromagnetic Fields on the Fertility System: Protocol for a Systematic Review and Meta-Analysis.
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Jan 1, 2018
This article presents a protocol for a systematic review and meta-analysis on radiofrequency electromagnetic field exposure from electronic devices and effects on the fertility system. The authors cite growing public concern and conflicting findings in prior studies as motivation. The protocol plans broad database…
Extremely low-frequency electromagnetic fields accelerates wound healing modulating MMP-9 and inflammatory cytokines.
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RF Safe Research Library
Jan 1, 2018
This in vitro study used a scratch wound model in human immortalized keratinocytes (HaCaT) to examine effects of extremely low-frequency electromagnetic fields (ELF-EMF). ELF-EMF exposure was reported to accelerate wound closure compared with sham and to increase inflammatory cytokine expression/release. The authors…
Extremely low-frequency electromagnetic field (EMF) generates alterations in the synthesis and secretion of oestradiol-17β (E) in uterine tissues: An in vitro study.
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RF Safe Research Library
Jan 1, 2018
This in vitro study exposed porcine endometrial and myometrial slices to extremely low-frequency EMF (50 or 120 Hz, 8 mT) for 2 or 4 hours, with or without progesterone. The authors report frequency- and time-dependent changes in oestradiol-17β secretion and CYP19A3 mRNA expression, with fewer changes when…
Effects of extremely low frequency electromagnetic fields on turkeys.
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RF Safe Research Library
Jan 1, 2018
This animal study exposed turkeys to ELF electromagnetic fields (50 Hz, 10 μT) for 3 weeks and assessed norepinephrine-activated β-adrenoceptor function via cAMP measurements over time. The authors report a time-dependent decrease in β-adrenoceptor function in exposed birds, while serum toxicological parameters…
Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.
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RF Safe Research Library
Jan 1, 2018
This in vitro study exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at SAR 6 W/kg for 2 hours per day over 3 days. RF-EMF exposure reduced mRNA levels of several Aβ-processing genes in HT22 cells, but did not change APP mRNA in SH-SY5Y cells. Protein levels of…
NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595
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RF Safe Research Library
Jan 1, 2018
This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…
Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats
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RF Safe Research Library
Mar 1, 2017
This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…
Effects of radiofrequency radiation in the presence of gold nanoparticles for the treatment of renal cell carcinoma.
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RF Safe Research Library
Jan 1, 2017
This in vitro study evaluated radiofrequency (RF) radiation with and without gold nanoparticles in human embryonic kidney (HEK) cancer cells as a potential approach for renal cell carcinoma treatment. The authors report reduced cell survival in one RF-exposed group versus control, and additional reductions in…
Radiofrequency Pulmonary Vein Isolation in a Patient with Dextrocardia With Situs Inversus Totalis.
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RF Safe Research Library
Jan 1, 2017
This case report describes radiofrequency pulmonary vein isolation in a 67-year-old man with dextrocardia and situs inversus totalis. The procedure successfully isolated all pulmonary veins using 3D mapping with intracardiac echocardiography guidance. No procedural complications were reported, and the authors…
The effects of electromagnetic fields on B16-BL6 cells are dependent on their spatial and temporal character.
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RF Safe Research Library
Jan 1, 2017
This in vitro study tested several complex low-intensity, low-frequency EMF patterns on proliferation of B16-BL6 mouse melanoma cells. A specific pattern (Thomas-EMF) with a 3 ms point duration reportedly inhibited proliferation and increased calcium uptake, while other timing settings did not. The authors conclude…
Effects of electromagnetic fields on bone loss in hyperthyroidism rat model.
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RF Safe Research Library
Jan 1, 2017
This animal study evaluated whether extremely low frequency EMF exposure affects bone loss in a levothyroxine-induced hyperthyroidism rat model. Rats exposed to 15 Hz/1 mT EMF plus levothyroxine showed improved bone mineral density, mechanical measures, and partially restored trabecular bone architecture compared…
Radiofrequency exposure in the Neonatal Medium Care Unit.
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RF Safe Research Library
Jan 1, 2017
This exposure assessment characterized RF-EMF levels in a Neonatal Medium Care Unit and inside incubators using spot and long-term dosimeter measurements. Reported levels varied by location (higher near a window and near the evaluated incubator) and by time (higher at night than during the day). The authors emphasize…
No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods.
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RF Safe Research Library
Jan 1, 2017
This animal study exposed pregnant Sprague-Dawley rats and their offspring to simultaneous whole-body multifrequency RF signals spanning 800 MHz to 5.2 GHz. Exposure occurred 20 hours per day from gestational day 7 to weaning, with F1 offspring exposed up to 6 weeks of age. Across multiple endpoints including growth,…
Effect of extremely low frequency electromagnetic field on brain histopathology of Caspian Sea Cyprinus carpio.
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RF Safe Research Library
Jan 1, 2017
This animal study evaluated 50 Hz extremely low frequency electromagnetic field exposure and brain histopathology in Cyprinus carpio. Fish were sham-exposed or exposed to magnetic field intensities from 0.1 to 7 mT for 0.5 or 1 hour. The authors report severe brain histopathological changes at intensities ≥3 mT,…
Effect of extremely low-frequency electromagnetic fields on antioxidant activity in the human keratinocyte cell line NCTC 2544.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human keratinocyte cells (NCTC 2544) to 50 Hz ELF-EMF at 0.25–2 G and assessed oxidative stress-related endpoints. Significant increases in ROS were reported at 0.5 and 1 G, with associated short-term changes in antioxidant and lipid peroxidation markers. The authors report that…
Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation.
Research
RF Safe Research Library
Jan 1, 2017
This study assessed whether adding extremely low-frequency electromagnetic field (ELF-EMF) exposure to a 4-week poststroke rehabilitation program affects nitric oxide (NO)-related biomarkers and patient status. Forty-eight poststroke patients were assigned to ELF-EMF versus non-ELF-EMF rehabilitation, with the…