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Showing results for: amplitude

Exposure of human lymphocytes to sweeping-frequency extremely low frequency magnetic field

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed human umbilical cord blood lymphocytes to a sinusoidal sweeping-frequency ELF magnetic field (3–26 Hz) for 48 hours at amplitudes from 6 to 24 μT. It reports no statistically significant effects on DNA damage/repair foci or apoptosis measures overall. A non-significant trend at 8 μT showed…

The proliferation rates of HT-1080 human fibrosarcoma cells can be accelerated or inhibited by weak static and extremely low frequency magnetic fields

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed HT-1080 human fibrosarcoma cells for 4 days to weak extremely low frequency magnetic fields (10 μT, 12–33 Hz) superimposed on a 45 μT static field. The authors report frequency- and amplitude-dependent increases or decreases in cell growth, including sharp inversions near 16.5 Hz with…

Effects of Mobile Electromagnetic Exposure on Brain Oscillations and Cortical Excitability: Scoping Review

Research RF Safe Research Library Jan 1, 2025

This scoping review evaluates evidence on mobile phone electromagnetic exposure and its effects on brain oscillations and cortical excitability in healthy individuals. Across 78 EEG studies (and 2 TMS studies), the authors report that exposure may be linked to changes in neural activity, including increased…

Impact of a Terahertz electromagnetic field on the ion permeation of potassium and sodium channels

Research RF Safe Research Library Jan 1, 2025

This biophysics study used molecular dynamics simulations to examine how terahertz electromagnetic fields affect ion permeation in voltage-gated potassium (Kv1.2) and sodium (Nav1.5) channels. The simulations report increased ion permeability at several specific terahertz frequencies, with effects depending on field…

Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields.

Research RF Safe Research Library Jan 1, 2025

This study reports that glioblastoma-specific amplitude-modulated 27.12 MHz RF electromagnetic fields (delivered intrabuccally) inhibited proliferation in several glioblastoma cell lines exposed 3 hours/day at patient-matched levels. The authors propose a mechanism involving CACNA1H and modulation of the “Mitotic…

It is the Frequency that Matters: Effects of Electromagnetic Fields on the Release and Content of Extracellular Vesicles.

Research RF Safe Research Library Jan 1, 2023

This preprint describes an in vitro bioreactor-based system to test whether electromagnetic/electrical stimulation affects extracellular vesicles (EVs). Using proteomics and single-vesicle flow cytometry, the authors report that stimulation at physiological current amplitudes can modulate EV content in a…

Low-energy amplitude-modulated electromagnetic field exposure: Feasibility study in patients with hepatocellular carcinoma.

Research RF Safe Research Library Jan 1, 2023

This single-site feasibility trial evaluated repeated 90-minute amplitude-modulated EMF exposure (AutEMdev) in 66 patients with advanced hepatocellular carcinoma. The primary focus was safety and hemodynamic variability during exposure, with exploratory outcomes including quality of life, survival, and tumor…

Low-energy amplitude-modulated radiofrequency electromagnetic fields as a systemic treatment for cancer: Review and proposed mechanisms of action

Research RF Safe Research Library Sep 8, 2022

This review discusses low-energy amplitude-modulated RF EMF (27.12 MHz carrier with low Hz–kHz envelope modulation) delivered systemically via intrabuccal antenna devices as a potential treatment for advanced hepatocellular carcinoma. It reports preclinical inhibition of cancer growth in vitro and in mouse xenograft…

Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.

Research RF Safe Research Library Jan 1, 2021

This review examines temperature-independent (non-thermal) effects of RF and microwave electromagnetic fields, emphasizing antiproliferative effects relevant to oncology. It summarizes preclinical and clinical literature on conventional RF hyperthermia and amplitude-modulated RF hyperthermia and argues that evidence…

Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma

Research RF Safe Research Library Jan 1, 2021

This pooled case series evaluated amplitude-modulated 27.12 MHz RF EMF delivered via the TheraBionic P1 device (3 hours daily) in patients with advanced hepatocellular carcinoma, comparing outcomes to historical controls. The authors report longer median overall survival for Child-Pugh A patients versus comparable…

A Novel In Vitro Device to Deliver Induced Electromagnetic Fields to Cell and Tissue Cultures.

Research RF Safe Research Library Jan 1, 2020

This paper presents an in vitro, noncontact solenoid-coil device designed to deliver intermediate-frequency induced electromagnetic fields that generate electric fields in cell and tissue cultures. The system aims to improve field characterization and reduce conductive heating compared with electrode-based approaches…

Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF

Research RF Safe Research Library Jan 1, 2019

This study describes a therapeutic use of athermal, amplitude-modulated RF EMF (27.12 MHz) at breast cancer-specific frequencies to target breast cancer brain metastases. The abstract reports tumor growth suppression in animal models and durable regression in one patient with triple negative breast cancer brain…

Geobacter sulfurreducens-inoculated bioelectrochemical system reveals the potential of metabolic current in defining the effect of extremely low-frequency electromagnetic field on living cells.

Research RF Safe Research Library Jan 1, 2019

This laboratory study exposed a Geobacter sulfurreducens-inoculated bioelectrochemical system to 0–128 Gauss extremely low-frequency electromagnetic fields. The authors report increased and oscillatory metabolic current under ELF-EMF exposure, with dose-dependent effects and a linear relationship between oscillation…

Early exposure to radiofrequency electromagnetic fields at 1850 MHz affects auditory circuits in early postnatal mice.

Research RF Safe Research Library Jan 1, 2019

This animal study examined early postnatal mice after exposure to 1850 MHz RF-EMF and measured synaptic activity in brainstem auditory circuitry. The abstract reports increased spontaneous postsynaptic current frequency and amplitude in MNTB principal cells, with accompanying presynaptic changes in the calyx of Held…

Hepatocellular carcinoma therapy finds a channel on the radio

Research RF Safe Research Library Jan 1, 2019

This EBioMedicine commentary discusses tumour-specific amplitude-modulated RF EMF as an anti-cancer therapy for hepatocellular carcinoma and highlights Cav3.2 (CACNA1H) T-type calcium channels as a proposed mediator of the effect. It notes that the reported whole-body averaged SAR in a treated HCC patient was below…

Effect of acute exposure to radiofrequency electromagnetic fields emitted by a mobile phone (GSM 900 MHz) on electrodermal responsiveness in healthy human.

Research RF Safe Research Library Jan 1, 2018

This study examined whether acute GSM 900 MHz mobile phone exposure affects electrodermal activity responses to auditory stimuli in 28 young volunteers. The authors report no exposure-related changes in SCR latency, amplitude, integral, or number of responses. Session differences in skin conductance/tonic…

Does acute radio-frequency electromagnetic field exposure affect visual event-related potentials in healthy adults?

Research RF Safe Research Library Jan 1, 2018

This double-blind, randomized, counterbalanced study tested whether acute GSM-like 920 MHz RF-EMF exposure affects visual event-related potentials in 36 healthy adults. Compared with sham, exposure was associated with reduced P1 amplitude and increased anterior N1 latency, with no effects on other ERP measures. The…

Microwave radiation alters burn injury-evoked electric potential in Nicotiana benthamiana.

Research RF Safe Research Library Jan 1, 2018

This plant study examined whether 2.45 GHz continuous-wave microwave exposure affects electric signaling in Nicotiana benthamiana after leaf burning. The authors report a significant reduction in the amplitude of the injury-evoked variation potential, mainly due to a reduced depolarization rate. The reported effect…

A Route to Chaotic Behavior of Single Neuron Exposed to External Electromagnetic Radiation.

Research RF Safe Research Library Jan 1, 2017

This computational study investigates nonlinear membrane-potential dynamics in a Fitzhugh-Nagumo single-neuron model that includes an external electromagnetic radiation term. The authors report that increasing the frequency of an external transmembrane current leads to mode selection among periodic, quasi-periodic,…

Efficient DNA ligation by selective heating of DNA ligase with a radio frequency alternating magnetic field.

Research RF Safe Research Library Jan 1, 2016

This in vitro study describes a method to improve DNA ligation by immobilizing T4 DNA ligase on ferromagnetic particles and applying a radio frequency alternating magnetic field. The field causes the particles to dissipate heat, which the authors report selectively heats and activates the ligase while minimally…

Targeted Magnetic Nanoparticles for Mechanical Lysis of Tumor Cells by Low-Amplitude Alternating Magnetic Field.

Research RF Safe Research Library Jan 1, 2016

This animal and in vitro study reports a method to lyse tumor cells mechanically using targeted superparamagnetic iron oxide nanoparticles rotated by a weak alternating magnetic field. Nude mice with head and neck tumors received cetuximab-coated nanoparticles and 4 Hz field exposures for 30 minutes on alternating…

Effect Of Electromagnetic Waves Emitted From Mobile Phone On Brain Stem Auditory Evoked Potential In Adult Males.

Research RF Safe Research Library Jan 1, 2015

This study examined whether electromagnetic waves from a mobile phone affect brainstem auditory evoked potentials (BAEP) in adult males aged 20–40 years. The right ear was exposed for about 10 minutes and BAEP measures were compared before and after exposure. The abstract reports significant changes in several BAEP…

Effects of extremely low-frequency electric fields at different intensities and exposure durations on mismatch negativity

Research RF Safe Research Library Jul 11, 2014

This rat study examined whether 50-Hz extremely low-frequency electric fields at 12 or 18 kV/m for 2 or 4 weeks affect mismatch negativity (MMN) and markers of oxidative damage/apoptosis in brain tissue. MMN amplitude was reported to be significantly reduced only in the 18 kV/m, 4-week exposure group versus the…

Effect of Bluetooth headset and mobile phone electromagnetic fields on the human auditory nerve.

Research RF Safe Research Library Jan 1, 2014

This randomized trial assessed short-term effects of electromagnetic fields from a mobile phone versus a Bluetooth headset on cochlear nerve activity during vestibular neurectomy in 12 patients. Bluetooth headset exposure showed no significant change in CNAP amplitude or latency. Direct mobile phone exposure was…

Electron-phonon bound states in graphene in a perpendicular magnetic field.

Research RF Safe Research Library Jan 1, 2012

This theoretical/physics study analyzes the spectrum of electron-phonon complexes in monolayer graphene in a perpendicular quantizing magnetic field. It reports that near the threshold of optical phonon emission, standard perturbation theory fails for calculating the scattering amplitude. The authors describe new…

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