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Filters: category: Therapeutic EMF Clear

Modulation of inflammatory response by electromagnetic field in Neuronal and Microglial cells.

Research RF Safe Research Library Jan 1, 2025

This in vitro study examined whether low-frequency electromagnetic field (EMF) stimulation modulates inflammatory signaling in neuronal and microglial cell lines after induction of a pro-inflammatory state with TNF-α. The authors report reduced transcriptional expression of inflammatory target genes at 24 and 48…

Effect of Electromagnetic Field on Proliferation and Migration of Fibroblasts and Keratinocytes: Implications in Wound Healing and Regeneration.

Research RF Safe Research Library Jan 1, 2024

This narrative review discusses reported effects of EMF, including low-frequency EMF (LF-EMF), on cell behaviors relevant to wound healing and on recovery processes after traumatic brain injury (TBI). It summarizes literature suggesting EMF can promote migration and proliferation of fibroblasts, keratinocytes, and…

Promising applications of electromagnetic field therapy in dental implantology: A systematic review.

Research RF Safe Research Library Jan 1, 2024

This systematic review assessed interventional preclinical and clinical studies of adjunctive non-ionizing magnetic or combined EMF therapies in dental implant surgery. Twelve studies were included, with most reporting improvements in implant stability and indicators of osteogenesis/osseointegration. Evidence for…

Chronic Drug-Resistant Cystitis Treated with a Sequence of Modulated Extremely Low-Frequency Electromagnetic Fields: A Randomized Study of 148 Cases.

Research RF Safe Research Library Jan 1, 2024

This randomized placebo-controlled study evaluated sequenced, modulated extremely low-frequency electromagnetic fields for drug-resistant chronic bacterial cystitis in 148 women. The treated group showed significant between-group differences at 4 weeks in multiple laboratory parameters, with reported sustained…

Electromagnetic Field Stimulation Therapy for Alzheimer's Disease.

Research RF Safe Research Library Jan 1, 2024

This review discusses repeated electromagnetic field stimulation (REMFS) as a potential non-invasive therapy for Alzheimer's disease. The abstract describes reported benefits in AD mice, including reduced beta-amyloid, prevention of neuronal death, halted disease progression, and improved memory without edema or…

Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study used a Yucatan miniswine model of traumatic brain injury with and without EMF stimulation to examine differential gene expression in injured versus non-injured cortex tissue. The authors report multiple differentially expressed genes linked to immune infiltration, myelination, oxidative stress…

EMAGINE-Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke.

Research RF Safe Research Library Jan 1, 2023

This paper presents the protocol for the EMAGINE multicenter, double-blind, randomized, sham-controlled trial testing an extremely low-frequency, low-intensity, frequency-tuned electromagnetic field therapy (ENTF) after subacute ischemic stroke. Participants will start active or sham treatment 4–21 days post-stroke,…

Frequency-tuned electromagnetic field therapy improves post-stroke motor function: A pilot randomized controlled trial.

Research RF Safe Research Library Jan 1, 2022

This pilot randomized, sham-controlled, double-blind trial evaluated extremely low frequency, low-intensity ENTF electromagnetic field therapy in subacute ischemic stroke patients with impaired upper extremity function. The per-protocol results reported greater improvements in motor function and disability outcomes…

Hydrogel-hydroxyapatite-monomeric collagen type-I scaffold with low-frequency electromagnetic field treatment enhances osteochondral repair in rabbits.

Research RF Safe Research Library Jan 1, 2021

This animal and in vitro study evaluated a composite osteochondral scaffold with bone marrow mesenchymal stem cells (BMSCs) combined with low-frequency electromagnetic field (EMF) stimulation. The authors report that EMF promoted BMSC proliferation and chondrogenic differentiation in vitro, partly via PI3K/AKT/mTOR…

A New Treatment for Stretch Marks and Skin Ptosis with Electromagnetic Fields and Negative Pressure: A Clinical and Histological Study.

Research RF Safe Research Library Jan 1, 2021

This clinical and histological study evaluated a combined electromagnetic fields and negative pressure treatment (V-EMF) for stretch marks and skin hypotonia. Sixty women aged 25–45 underwent 6 or 8 weekly sessions, with documentation via pictures, patient satisfaction, and biopsies. The authors report histological…

A Prospective Comparative Study of Pulsed High-Intensity Laser Therapy and Pulsed Electromagnetic Field on Chronic Nonspecific Low Back Pain.

Research RF Safe Research Library Jan 1, 2021

This prospective comparative study randomized 51 adults with chronic nonspecific low back pain into HILT, pulsed EMF, or control groups for 8 weeks of treatment (twice weekly). Both HILT and EMF groups showed improvements in pain, disability, and lumbar flexion range of motion after the intervention. The study…

Effects of electromagnetic fields treatment on rat critical-sized calvarial defects with a 3D-printed composite scaffold.

Research RF Safe Research Library Jan 1, 2020

This animal and in vitro study evaluated electromagnetic fields (EMF) treatment combined with a 3D-printed PLA/HA scaffold seeded with rat bone marrow mesenchymal stem cells (BMSCs) for cranial defect repair. The authors report that EMF enhanced BMSC proliferation and osteogenic differentiation and was partly…

A single-pulsed electromagnetic field enhances collagen synthesis in tendon cells.

Research RF Safe Research Library Jan 1, 2020

This in vitro study reports that a single pulsed electromagnetic field (0.2 Hz) increased expression of tenogenic genes and reduced expression of a matrix-degradation/inflammatory gene (Mmp1) in tendon cells. After 5 days of exposure (3 min/day), collagen type I and total collagen synthesis protein levels were…

Emerging medical applications based on non-ionizing electromagnetic fields from 0 Hz to 10 THz.

Research RF Safe Research Library Jan 1, 2019

This review discusses medical applications of non-ionizing electromagnetic fields spanning 0 Hz to the THz range, focusing mainly on therapeutic uses and mentioning few diagnostic approaches. It reports that current EMF-based methods generally have limited clinical impact and are not expected to replace conventional…

The influence of low-frequency variable magnetic fields in reducing pain experience after dental implant treatment.

Research RF Safe Research Library Jan 1, 2015

This study evaluated magnetostimulation and magnetoledtherapy for pain reduction after dental implant treatment in three groups of 10 patients each. Pain was recorded using a VAS scale, and analgesic use was also tracked. The abstract reports lower pain scores and reduced analgesic use in the magnetostimulation…

An open-label pilot study of pulsed electromagnetic field therapy in the treatment of failed back surgery syndrome pain.

Research RF Safe Research Library Jan 1, 2015

This open-label exploratory pilot study evaluated pulsed electromagnetic field therapy given twice daily for 45 days in 34 people with persistent or recurrent pain after back surgery. Among 30 per-protocol completers, 33% met a responder definition of ≥30% pain intensity reduction, and pain improvements were reported…

Effect of pulsed electromagnetic field therapy in patients undergoing total knee arthroplasty: a randomised controlled trial

Research RF Safe Research Library Jan 1, 2014

This randomized controlled trial compared postoperative pulsed electromagnetic field therapy (I-ONE) versus control in 33 patients undergoing total knee arthroplasty. The treated group reported significantly better pain, swelling, and functional scores at 1 month, with lower pain still present at 6 months. At 3…

Pulsed electromagnetic field and exercises in patients with shoulder impingement syndrome: a randomized, double-blind, placebo-controlled clinical trial

Research RF Safe Research Library Jan 1, 2014

This double-blind randomized placebo-controlled trial evaluated pulsed electromagnetic field (PEMF) therapy followed by a standardized shoulder strengthening exercise program in adults with shoulder impingement syndrome (N=56). The active PEMF group improved in pain and function from baseline across follow-ups, while…

Radiodensitometric Assessment of the Effect of Pulsed Electromagnetic Field Stimulation Versus Low Intensity Laser Irradiation on Mandibular Fracture Repair: A Preliminary Clinical Trial.

Research RF Safe Research Library Jan 1, 2014

This preliminary prospective clinical trial compared pulsed electromagnetic field stimulation (PEMF) and low intensity laser irradiation (LILI) as adjuncts to mandibular fracture repair assessed by clinical union and radiodensitometric bone density. Clinical outcomes (segment stability and occlusion) were…

Optimization of a therapeutic electromagnetic field (EMF) to retard breast cancer tumor growth and vascularity.

Research RF Safe Research Library Jan 1, 2014

This animal study evaluated a therapeutic 120 Hz pulsed EMF device (10–20 mT) in C3H mice bearing implanted murine mammary adenocarcinoma tumors. Across seven treated groups, EMF exposure over 12 days was reported to suppress tumor growth, with specific dose/time regimens described as most effective. The authors also…

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