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The exposure to extremely low frequency electromagnetic-fields inhibits the growth and potentiates the sensitivity to chemotherapy of bidimensional and tridimensional human osteosarcoma models.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested a specific extremely low frequency electromagnetic field (ELF-EMF) on three human osteosarcoma cell lines grown in 2D and 3D spheroid models. The abstract reports that ELF-EMF exposure inhibited proliferation and altered mitochondrial metabolism in the cancer models. It also reports…

The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…

The impact of electromagnetic fields generated by high-voltage power lines on the spatial arrangement of pike (Esox Lucius Linnaeus 1758) embryos.

Research RF Safe Research Library Jan 1, 2024

This animal study incubated fertilized pike eggs under electromagnetic fields associated with high-voltage transmission lines (110 kV and 220 kV) and compared them with a control group without anthropogenic EMF. The authors report no significant effect of HVTL-related EMF on embryo orientation and conclude survival…

Extremely low-frequency electromagnetic field (ELF-EMF) induced alterations in gene expression and cytokine secretion in clear cell renal carcinoma cells.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed three ccRCC cell lines and a healthy kidney cell line (HEK293) to 50 Hz ELF-EMF at 4.5 mT for 30 minutes daily over 5 days. The authors report exposure-associated changes in expression of several genes (names not fully visible in the abstract), with differences between primary…

Effect of rmEGF combined with ELF-EMF on promoting wound healing in rats.

Research RF Safe Research Library Jan 1, 2024

This randomized animal study evaluated whether recombinant murine EGF combined with ELF-EMF improves wound healing in rats. The combined ELF-EMF+rmEGF group showed better wound healing rates and more favorable histological features than comparison groups at multiple time points. All groups had complete wound closure…

Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices from days 15–16 of pregnancy to a 50 Hz extremely low-frequency electromagnetic field for 2 hours. The authors report changes in several epigenetic-related markers, including DNA methylation machinery, histone-related measures (HDAC activity), global DNA…

Effect of soil pH on thermally enhanced desorption of m-xylene by zero-valent iron particles under an electromagnetic field.

Research RF Safe Research Library Jan 1, 2023

This laboratory/engineering study evaluated thermally enhanced desorption of m-xylene from soil using heat generated by zero-valent iron (ZVI) under low-frequency electromagnetic fields. The abstract reports rapid heating (to ~60°C in 20 minutes) and substantially lower residual m-xylene after 60 minutes versus soil…

Osteogenic effect of electromagnetic fields on stem cells derived from rat bone marrow cultured in osteogenic medium versus conditioned medium in vitro.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested whether ELF-EMF exposure (50 Hz, 1 mT; 30 min/day) influences osteogenic differentiation markers in rat bone-marrow-derived stem cells cultured in osteogenic medium or in human adipose-stem cell-conditioned medium. The OM + EMF condition showed higher ALP activity and higher Runx2 and Ocn…

CaATPase enzyme activities and lipid and protein oxidations of grass carp (Ctenopharyngodon idellus) stored at 4 °C for 30 min under electromagnetic fields.

Research RF Safe Research Library Jan 1, 2023

This study evaluated 12 mT electromagnetic fields (100–400 Hz) applied during 30 minutes of cold storage (4 °C) of grass carp. EMF exposure was associated with increased CaATPase activity and frequency-dependent changes in protein and lipid oxidation. NMR results suggested altered water–protein interactions, and the…

NET Formation Was Reduced via Exposure to Extremely Low-Frequency Pulsed Electromagnetic Fields.

Research RF Safe Research Library Jan 1, 2023

This in vitro study examined whether a 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) affects neutrophil extracellular trap (NET) formation. In neutrophils from healthy volunteers, ELF-PEMF exposure did not induce ROS or calcium influx and did not increase basal or PMA-induced NET formation.…

The Effect of Low-Frequency Pulsed Electromagnetic Fields on the Differentiation of Permanent Dental Pulp Stem Cells into Odontoblasts.

Research RF Safe Research Library Jan 1, 2023

This in vitro study exposed dental pulp mesenchymal stem cells to 50 Hz pulsed electromagnetic fields at 0.5 or 1 mT for 20 or 40 minutes per day over seven days. Cell survival/proliferation was generally higher than control across exposure groups, except for the 40 minutes/day at 1 mT condition. DMP1 expression was…

The Effect of Extremely Low-Frequency Electromagnetic Fields on Inflammation and Performance-Related Indices in Trained Athletes: A Double-Blinded Crossover Study.

Research RF Safe Research Library Jan 1, 2023

This double-blinded crossover study tested an ELF-EMF mattress used immediately after high-intensity cycling and overnight in nine trained male athletes. The authors report no significant overall effects on performance and inflammation. However, between 60 minutes and 24 hours post-exercise, the active condition…

Phagocytosis of latex beads by a human monocytic Mono Mac 6 cell line and effects of low-frequency electromagnetic field interaction.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested whether a low-frequency EMF (7 Hz, 30 mT) alters phagocytosis-related outcomes in the human monocytic Mono Mac 6 cell line. EMF exposure was associated with increased necrosis in cells pre-stimulated with SEB and then undergoing latex bead phagocytosis, while no significant cell-death…

P53 status, and G2/M cell cycle arrest, are determining factors in cell-death induction mediated by ELF-EMF in glioblastoma.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested ELF-EMF exposure in U87 and U251 glioblastoma cell lines and assessed apoptosis, cell-cycle distribution, cell size, and mRNA expression of cell-cycle genes. The authors report higher apoptosis induction and increased G2/M arrest in U87 compared with U251, alongside increased U87 cell size…

Extremely low-frequency electromagnetic field exposure alters DNA methylation levels in the endometrium of pigs during the peri-implantation period.

Research RF Safe Research Library Jan 1, 2023

This in vitro study exposed porcine endometrial slices from the peri-implantation period (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed promoter DNA methylation in selected genes. The authors report increased methylation for EGR2, ID2, and PTGER4, decreased methylation for IL1RAP and NOS3, and no…

Transcriptome profiling of flax plants exposed to a low-frequency alternating electromagnetic field.

Research RF Safe Research Library Jan 1, 2023

This study aims to perform transcriptome profiling in flax plants exposed to a low-frequency alternating electromagnetic field. The abstract frames prior work as suggesting EMF-related changes in free radical homeostasis and altered expression of genes involved in stress responses, ion transport, and cell wall…

Synergistic cytotoxic effects of an extremely low-frequency electromagnetic field with doxorubicin on MCF-7 cell line.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested whether a 50 Hz, 20 mT extremely low-frequency electromagnetic field (ELF-EMF) enhances the cytotoxic effects of doxorubicin (DOX) in the MCF-7 breast cancer cell line. The authors report that combining ELF-EMF with low-dose DOX reduced cell viability at lower DOX concentrations than DOX…

EMAGINE-Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke.

Research RF Safe Research Library Jan 1, 2023

This paper presents the protocol for the EMAGINE multicenter, double-blind, randomized, sham-controlled trial testing an extremely low-frequency, low-intensity, frequency-tuned electromagnetic field therapy (ENTF) after subacute ischemic stroke. Participants will start active or sham treatment 4–21 days post-stroke,…

Measuring and assessing the effects of extremely low-frequency electromagnetic fields (ELF-EMF) on blood parameters and liver enzymes of personnel working in high voltage power stations in a petrochemical industry.

Research RF Safe Research Library Jan 1, 2023

This cross-sectional study in a petrochemical industry compared 50 high-voltage power-station workers exposed to ELF-EMF with 50 controls. Electric and magnetic fields were measured at 200 points, and blood parameters and liver enzymes were extracted from medical records. The study reports no significant differences…

Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study.

Research RF Safe Research Library Jan 1, 2023

This animal study evaluated ketamine administration combined with extremely low-frequency electromagnetic field (ELF-EMF) exposure in a chronic unpredictable stress (CUS) rat model. The authors report that the combined treatment increased depression-like behavior and neuronal degeneration, reduced GFAP(+) cells in…

Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca Influx in Osteoprogenitor Cells.

Research RF Safe Research Library Jan 1, 2023

This in vitro study compared continuous versus intermittent 16 Hz ELF-PEMF exposure strategies in osteoprogenitor (SCP-1) cells. Intermittent exposure (10 min every 8 h) was reported to enhance cell numbers and osteogenic function relative to continuous daily exposure (30 min every 24 h). The authors report increased…

The effect of the electromagnetic field on the physicochemical properties of isolated corn starch obtained of plants from irradiate seeds.

Research RF Safe Research Library Jan 1, 2023

This study examined whether exposing maize seeds to electromagnetic fields (23, 70, 118 μT) for 15 days alters physicochemical properties of starch isolated from the resulting grains. SEM and X-ray diffraction results suggest starch morphology and orthorhombic crystalline structure were largely unchanged, though…

Effect of extremely low frequency electromagnetic field on the pathogenicity of Magnaporthe oryzae.

Research RF Safe Research Library Jan 1, 2023

This laboratory study examined Magnaporthe oryzae pathogenicity under extremely low frequency electromagnetic field exposure (50 Hz, 3 mT). The authors report increased infection ability, growth rate, and conidia generation with ELF-EMF exposure. They also report increased tolerance to a cell wall-perturbing agent…

Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).

Research RF Safe Research Library Jan 1, 2023

This in vitro study assessed 50 Hz, 100 G extremely low-frequency EMF in combination with temozolomide and radiation in T98 glioblastoma cells grown as monolayers and spheroids. Radiation plus EMF increased apoptosis-related gene expression, while temozolomide plus EMF increased autophagy marker expression compared…

The Effect of Time-Dependence of 10 Hz Electromagnetic Field on Spatial Learning and Memory in Rats.

Research RF Safe Research Library Jan 1, 2022

This animal study exposed 40 adult male rats to a 10 Hz (4 mT) extremely low-frequency electromagnetic field for 1 hour daily for either 7 or 30 days. The authors report improved spatial memory after prolonged (30-day) exposure, alongside increased hippocampal BDNF levels. They also note a significant body weight…

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