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Filters: category: Clinical Trials Clear

Efficacy of nonablative radiofrequency on sexual function in postmenopausal women: a randomized clinical trial.

Research RF Safe Research Library Jan 1, 2026

This single-blind randomized controlled trial evaluated nonablative capacitive-resistive monopolar radiofrequency versus sham in postmenopausal women with genitourinary syndrome of menopause. The intervention group reported significantly greater improvements in sexual function (FSFI) and vaginal health (VHI) at…

Chronic Drug-Resistant Cystitis Treated with a Sequence of Modulated Extremely Low-Frequency Electromagnetic Fields: A Randomized Study of 148 Cases.

Research RF Safe Research Library Jan 1, 2024

This randomized placebo-controlled study evaluated sequenced, modulated extremely low-frequency electromagnetic fields for drug-resistant chronic bacterial cystitis in 148 women. The treated group showed significant between-group differences at 4 weeks in multiple laboratory parameters, with reported sustained…

EMAGINE-Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke.

Research RF Safe Research Library Jan 1, 2023

This paper presents the protocol for the EMAGINE multicenter, double-blind, randomized, sham-controlled trial testing an extremely low-frequency, low-intensity, frequency-tuned electromagnetic field therapy (ENTF) after subacute ischemic stroke. Participants will start active or sham treatment 4–21 days post-stroke,…

Low-energy amplitude-modulated electromagnetic field exposure: Feasibility study in patients with hepatocellular carcinoma.

Research RF Safe Research Library Jan 1, 2023

This single-site feasibility trial evaluated repeated 90-minute amplitude-modulated EMF exposure (AutEMdev) in 66 patients with advanced hepatocellular carcinoma. The primary focus was safety and hemodynamic variability during exposure, with exploratory outcomes including quality of life, survival, and tumor…

Frequency-tuned electromagnetic field therapy improves post-stroke motor function: A pilot randomized controlled trial.

Research RF Safe Research Library Jan 1, 2022

This pilot randomized, sham-controlled, double-blind trial evaluated extremely low frequency, low-intensity ENTF electromagnetic field therapy in subacute ischemic stroke patients with impaired upper extremity function. The per-protocol results reported greater improvements in motor function and disability outcomes…

A Prospective Comparative Study of Pulsed High-Intensity Laser Therapy and Pulsed Electromagnetic Field on Chronic Nonspecific Low Back Pain.

Research RF Safe Research Library Jan 1, 2021

This prospective comparative study randomized 51 adults with chronic nonspecific low back pain into HILT, pulsed EMF, or control groups for 8 weeks of treatment (twice weekly). Both HILT and EMF groups showed improvements in pain, disability, and lumbar flexion range of motion after the intervention. The study…

Effect of a Smartphone-Based App on the Quality of Life of Patients With Heart Failure: Randomized Controlled Trial.

Research RF Safe Research Library Jan 1, 2020

This randomized controlled trial evaluated whether adding a smartphone-based app to routine care improves quality of life in hospitalized patients with heart failure. Over 3 months, the app group reported significantly better quality-of-life scores than the control group on the Minnesota Living with Heart Failure…

Efficacy of Mobile Phone Short Message Service (SMS) Reminders on Malaria Treatment Adherence and Day 3 Post-Treatment Reviews (SMS-RES-MAL) in Kenya: A Study Protocol.

Research RF Safe Research Library Jan 1, 2019

This protocol describes a proof-of-concept open-label randomized controlled trial in Western Kenya assessing whether SMS reminders added to standard care improve malaria treatment adherence and day 3 post-treatment review attendance. Caregivers of children under five with uncomplicated malaria will be randomized to…

Efficacy of extremely low-frequency magnetic field in fibromyalgia pain: A pilot study.

Research RF Safe Research Library Jan 1, 2016

This pilot randomized study evaluated systemic extremely low-frequency magnetic field (ELF-MF) therapy versus sham in 37 women with fibromyalgia using a crossover sequence. The abstract reports significant short-term reductions in pain and improvements in fibromyalgia-related symptom and function questionnaires…

Pulsed electromagnetic field and exercises in patients with shoulder impingement syndrome: a randomized, double-blind, placebo-controlled clinical trial

Research RF Safe Research Library Jan 1, 2014

This double-blind randomized placebo-controlled trial evaluated pulsed electromagnetic field (PEMF) therapy followed by a standardized shoulder strengthening exercise program in adults with shoulder impingement syndrome (N=56). The active PEMF group improved in pain and function from baseline across follow-ups, while…

Radiodensitometric Assessment of the Effect of Pulsed Electromagnetic Field Stimulation Versus Low Intensity Laser Irradiation on Mandibular Fracture Repair: A Preliminary Clinical Trial.

Research RF Safe Research Library Jan 1, 2014

This preliminary prospective clinical trial compared pulsed electromagnetic field stimulation (PEMF) and low intensity laser irradiation (LILI) as adjuncts to mandibular fracture repair assessed by clinical union and radiodensitometric bone density. Clinical outcomes (segment stability and occlusion) were…

Effect of lansoprazole on the epigastric symptoms of functional dyspepsia (ELF study): A multicentre, prospective, randomized, double-blind, placebo-controlled clinical trial.

Research RF Safe Research Library Jan 1, 2013

This multicentre, randomized, double-blind, placebo-controlled trial in Japan evaluated lansoprazole 15 mg daily for 4 weeks in functional dyspepsia diagnosed by Rome III criteria. Lansoprazole showed higher overall symptom relief than placebo at week 4 and improved epigastric pain and burning scores. Postprandial…

Pulsed radiofrequency in peripheral posttraumatic neuropathic pain: A double blind sham controlled randomized clinical trial.

Research RF Safe Research Library Jan 1, 2012

This double-blind, randomized, sham-controlled trial evaluated pulsed radiofrequency applied to injured peripheral nerves for peripheral posttraumatic neuropathic pain. Among 43 analyzed participants, PRF did not show statistically significant benefit over sham for pain reduction at 3 months, nor for neuropathic pain…

Peripheral pulsed electromagnetic fields may reduce the placebo effect in migraine patients that do not respond to the sham intervention in a randomized, placebo-controlled, double-blind, cross-over clinical trial.

Research RF Safe Research Library Jan 1, 2012

This randomized, placebo-controlled, double-blind, cross-over trial evaluated a wrist-applied PEMF bracelet in 18 migraine patients and examined possible modulation of placebo effects. In the overall group, both PEMF and placebo were associated with similar reductions in migraine frequency and intensity. The authors…

Evaluation of the efficacy of pulsed electromagnetic field in the management of patients with diabetic polyneuropathy.

Research RF Safe Research Library Jan 1, 2009

This randomized controlled trial evaluated low-power, low-frequency pulsed electromagnetic field (PEMF) therapy at 600 Hz and 800 Hz as an adjunct treatment for diabetic polyneuropathy. Thirty participants were randomized to 600 Hz PEMF, 800 Hz PEMF, or usual medical treatment for 12 days. The abstract reports…

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