Archive

310 posts

Filters: category: Animal studies Clear

Ameliorative effects of crocin against electromagnetic field-induced oxidative stress and liver and kidney injuries in mice.

Research RF Safe Research Library Jan 1, 2023

This mouse experiment evaluated whether crocin (50 mg/kg) mitigates liver and kidney injury associated with 2100 MHz electromagnetic field exposure. EMF exposure was associated with increased serum markers of kidney and liver injury, reduced antioxidant enzyme activity, and histopathological/ultrastructural changes…

Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways.

Research RF Safe Research Library Jan 1, 2023

This animal study examined EMF exposure in a mouse high-fat diet model of NAFLD. The authors report that EMF exposure reduced hepatic lipid accumulation and markers of oxidative stress, alongside changes consistent with activation of CaMKKβ/AMPK and Nrf2-related signaling. The abstract concludes EMF could be a…

50 Hz Magnetic Field Exposure Inhibited Spontaneous Movement of Zebrafish Larvae through ROS-Mediated syn2a Expression.

Research RF Safe Research Library Jan 1, 2023

This zebrafish study exposed embryos to a 50 Hz magnetic field at 100–800 μT for 1 h or 24 h daily over 5 days. The authors report no changes in hatching, mortality, or malformation rates, but report reduced spontaneous movement at 200 μT along with brain histological abnormalities. They also report increased ROS and…

Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study.

Research RF Safe Research Library Jan 1, 2023

This animal study evaluated ketamine administration combined with extremely low-frequency electromagnetic field (ELF-EMF) exposure in a chronic unpredictable stress (CUS) rat model. The authors report that the combined treatment increased depression-like behavior and neuronal degeneration, reduced GFAP(+) cells in…

Hazardous effects of high voltage electromagnetic field on albino rats and protective role of Rosmarinus officinalis.

Research RF Safe Research Library Jan 1, 2022

This animal study examined effects of a 50 Hz high-voltage electromagnetic field (5.4 kV/m) applied 2 or 4 hours per day for 25 days in albino rats. The authors report decreases in RBC, haemoglobin, and catalase activity, with increases in WBCs, liver enzymes, bilirubin, kidney-related markers, and malondialdehyde…

The Effect of Time-Dependence of 10 Hz Electromagnetic Field on Spatial Learning and Memory in Rats.

Research RF Safe Research Library Jan 1, 2022

This animal study exposed 40 adult male rats to a 10 Hz (4 mT) extremely low-frequency electromagnetic field for 1 hour daily for either 7 or 30 days. The authors report improved spatial memory after prolonged (30-day) exposure, alongside increased hippocampal BDNF levels. They also note a significant body weight…

The Effect of 12 Hz Extremely Low-frequency Electromagnetic Field on Visual Memory of Male Macaque Monkeys.

Research RF Safe Research Library Jan 1, 2022

This animal experiment assessed visual memory, cortisol, GR gene expression, and amygdala volume in four male rhesus macaques exposed to a 12 Hz, 0.7 μT ELF magnetic field. The exposed monkeys reportedly showed improved visual memory and reduced serum cortisol and GR gene expression, while controls did not show…

Electromagnetic field stimulation facilitates motor neuron excitability, myogenesis and muscle contractility in spinal cord transected rats.

Research RF Safe Research Library Jan 1, 2022

This animal study evaluated whole-body EMF stimulation in a rat model of complete spinal cord injury. Compared with SCI alone, EMF exposure for 7 or 14 days was reported to improve electrophysiological measures of motor neuron excitability and enhance soleus muscle contractile performance. Histopathology and protein…

PIXE analysis of iron in rabbit cerebellum after exposure to radiofrequency electromagnetic fields.

Research RF Safe Research Library Jan 1, 2022

This animal study assessed iron in rabbit cerebellum after exposure to real GSM and generated RF electromagnetic fields using ICP MS and PIXE. ICP MS found no significant differences in overall iron concentration between exposed and control groups. PIXE reported focal iron accumulation up to about 3 mm, with the…

Bidirectional Effect of Repeated Exposure to Extremely Low-Frequency Electromagnetic Field (50 Hz) of 1 and 7 mT on Oxidative/Antioxidative Status in Rat's Brain: The Prediction for the Vulnerability to Diseases.

Research RF Safe Research Library Jan 1, 2022

This rat study examined repeated 50 Hz ELF-EMF exposure (1 or 7 mT) and measured oxidative stress and antioxidant defense markers in the prefrontal cortex, including responses to a subsequent open-field stressor. The authors report intensity- and repetition-dependent effects: 1 mT produced weak changes and was…

No evidence for collateral effects of electromagnetic fields used to increase dissolved oxygen levels on the behavior and physiology of freshwater fishes.

Research RF Safe Research Library Jan 1, 2022

This animal study evaluated whether low-intensity EMF devices used to increase dissolved oxygen have collateral effects on freshwater fish. In captive sunfish, the authors report no significant differences in stress physiology biomarkers, behavior, or putative aerobic capacity between EMF and control conditions over…

Changes in Free Radical Processes under the Influence of Low-Frequency Electromagnetic Field in Rats.

Research RF Safe Research Library Jan 1, 2022

This in vivo animal study examined how low-frequency electromagnetic field exposure affects antioxidant status in Wistar rats. The authors report frequency-dependent changes in antioxidant enzyme activity and hydroperoxide content in blood plasma. They also propose that LF EMF may stimulate low levels of ROS that…

Treatment with Pulsed Extremely Low Frequency Electromagnetic Field (PELF-EMF) Exhibit Anti-Inflammatory and Neuroprotective Effect in Compression Spinal Cord Injury Model.

Research RF Safe Research Library Jan 1, 2022

This animal study tested a pulsed extremely low frequency electromagnetic field (PELF-EMF) SEQEX device in a mouse compression spinal cord injury model. Mice received 4 hours of daily exposure for two months starting 2 hours after injury. The study reports reduced inflammatory and astrocyte activation markers,…

Comparing the Effects of Long-term Exposure to Extremely Low-frequency Electromagnetic Fields With Different Values on Learning, Memory, Anxiety, and β-amyloid Deposition in Adult Rats.

Research RF Safe Research Library Jan 1, 2021

This animal study exposed adult male rats to 50 Hz ELF-EMF at 1, 100, 500, or 2000 μT for 1 hour/day over two months and assessed behavior and brain markers. The authors report increased memory retention (higher step-through latency) alongside increased anxiety-like behavior (reduced open-arm entries), particularly…

Electromagnetic Field Stimulation Attenuates Phasic Nociception after Complete Spinal Cord Injury in Rats.

Research RF Safe Research Library Jan 1, 2021

This animal study evaluated whole-body extremely low-frequency EMF stimulation after thoracic complete spinal cord injury in adult male rats. The authors report reduced nociceptive behaviors (hyperalgesia/allodynia) from week 6 onward and restoration of spinal reflexes by week 8. They also report lower glutamate at…

Hydrogel-hydroxyapatite-monomeric collagen type-I scaffold with low-frequency electromagnetic field treatment enhances osteochondral repair in rabbits.

Research RF Safe Research Library Jan 1, 2021

This animal and in vitro study evaluated a composite osteochondral scaffold with bone marrow mesenchymal stem cells (BMSCs) combined with low-frequency electromagnetic field (EMF) stimulation. The authors report that EMF promoted BMSC proliferation and chondrogenic differentiation in vitro, partly via PI3K/AKT/mTOR…

Morphometric analysis - effect of the radiofrequency interface of electromagnetic field on the size of hatched Dermacentor reticulatus larvae.

Research RF Safe Research Library Jan 1, 2021

This animal study examined whether exposing Dermacentor reticulatus tick eggs to 900 MHz RF-EMF for 30, 60, or 90 minutes affects the size of hatched larvae. The authors report that the 60-minute exposure group produced larvae with larger measurements across four body traits compared with unexposed controls and other…

Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on male fertility and pregnancy and birth outcomes: Protocols for a systematic review of experimental studies in non-human mammals and in human sperm exposed in vitro.

Research RF Safe Research Library Jan 1, 2021

This paper presents protocols for a systematic review of experimental studies assessing RF-EMF exposure (100 kHz–300 GHz) and outcomes related to male fertility and pregnancy/birth effects. The review will cover three evidence streams: non-human mammal male reproductive outcomes, human sperm exposed in vitro, and in…

The Time-Dependence of Three Different Modes of ELF-EMF Stimulation on LTP at Schaffer Collateral-CA1 Synapses.

Research RF Safe Research Library Jan 1, 2021

This animal ex vivo study tested whether short-term 15 Hz/2 mT ELF-EMF exposure alters LTP at rat hippocampal SC-CA1 synapses. Across sinusoidal, pulsed, and rhythm-pulsed modes, the authors report reduced LTP versus control, with greater inhibition at longer exposure durations (10–60 s). Sinusoidal stimulation…

Effects induced by a 50 Hz electromagnetic field and doxorubicin on Walker-256 carcinosarcoma growth and hepatic redox state in rats.

Research RF Safe Research Library Jan 1, 2021

This animal study compared 50 Hz extremely low-frequency EMF exposure with doxorubicin (and their combination) in Walker-256 carcinosarcoma-bearing rats, assessing tumor growth and liver redox-related outcomes. DOX and DOX+EMF were reported to inhibit tumor growth more than EMF alone, though EMF alone also showed an…

Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice.

Research RF Safe Research Library Jan 1, 2021

This animal and primary neuron culture study exposed early postnatal mice to whole-body RF-EMF (SAR 4.0 W/kg) for 5 hours/day from P1 to P28. The authors report reductions in dendritic spine measures (notably mushroom-type spines), decreased glutamate receptor expression in mushroom-type spines, and lower BDNF…

Necroptosis triggered by ROS accumulation and Ca overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivo.

Research RF Safe Research Library Jan 1, 2021

This animal and in vitro study examined ELF magnetic field exposure in a mouse breast tumor model and a breast cancer cell line. The authors report tumor growth suppression and reduced expression of Ki-67, CD31, VEGFR2, and MMP-9 after exposure. They also report increased IFN-γ and TNF-α and increased…

Sinusoidal electromagnetic fields accelerate bone regeneration by boosting the multifunctionality of bone marrow mesenchymal stem cells.

Research RF Safe Research Library Jan 1, 2021

This in vitro and rat study evaluated sinusoidal electromagnetic field (EMF) treatment of bone marrow mesenchymal stem cells (BMSCs) seeded on 3D-printed scaffolds for repairing critical-sized calvarial defects. The authors report that EMF-treated cell scaffolds accelerated bone defect repair in rats.…

Evaluation of the neuroprotective effects of Vitamin E on the rat substantia nigra neural cells exposed to electromagnetic field: An ultrastructural study.

Research RF Safe Research Library Jan 1, 2021

This rat study exposed animals to a 50 Hz, 3 mT electromagnetic field and assessed oxidative stress markers and substantia nigra ultrastructure. EMF exposure was associated with higher lipid peroxidation (MDA), lower SOD activity, and TEM-detected changes in nucleus/nuclear membrane and myelin sheath. Vitamin E…

Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice.

Research RF Safe Research Library Jan 1, 2021

This animal study examined whether 8 weeks of EMF exposure affects insulin resistance and fatty liver features in db/db mice. The authors report improvements in insulin resistance markers, hepatic redox balance, and steatosis-related outcomes after EMF exposure. They also report reduced liver triglycerides and lower…

← Prev Page 6 / 13 Next →